[HTML][HTML] A novel PEG-mediated approach to entrap hemoglobin (Hb) within ZIF-8 nanoparticles: Balancing crystalline structure, Hb content and functionality

C Coll-Satue, M Rubio-Huertas, A Ducrot… - Biomaterials …, 2024 - Elsevier
Hemoglobin (Hb)-based oxygen carriers are investigated as a potential alternative or
supplement to regular blood transfusions, particularly in critical and life-threatening …

Nanomaterial-related hemoglobin-based oxygen carriers, with emphasis on liposome and nano-capsules, for biomedical applications: current status and future …

K Zhu, L Wang, Y Xiao, X Zhang, G You, Y Chen… - Journal of …, 2024 - Springer
Oxygen is necessary for life and plays a key pivotal in maintaining normal physiological
functions and treat of diseases. Hemoglobin-based oxygen carriers (HBOCs) have been …

[HTML][HTML] Comparative evaluation of UV-Vis spectroscopy-based approaches for hemoglobin quantification: method selection and practical insights

C Coll-Satue, MMT Jansman, L Hosta-Rigau - Biomolecules, 2024 - mdpi.com
The growing demand for effective alternatives to red blood cells (RBCs) has spurred
significant research into hemoglobin (Hb)-based oxygen carriers (HBOCs). Accurate …

Stability assessment in aqueous and organic solvents of metal–organic framework PCN 333 nanoparticles through a combination of physicochemical characterization …

X Liu, A Ortega-Guerrero, N P. Domingues, MJ Pougin… - Langmuir, 2024 - ACS Publications
Mesoporous metal–organic frameworks (MOFs) have been recognized as powerful
platforms for drug delivery, especially for biomolecules. Unfortunately, the application of …

Protein-templated metal nanoclusters for chemical sensing

HW Chu, GG Demissie, CC Huang… - Frontiers in Analytical …, 2025 - frontiersin.org
Metal nanoclusters (MNCs) possess unique optical properties, discrete energy levels,
biocompatibility and photostability, making them pivotal photoluminescent probes in …

In vitro and in vivo investigations of hemoglobin-loaded PEGylated ZIF-8 nanoparticles as oxygen carriers for emergency transfusion

G Bor, W Jin, D Douka, NJ Borthwick, X Liu… - Biomaterials …, 2025 - Elsevier
The limitations of traditional blood supply systems, particularly where ideal storage is
unfeasible, challenge the efficacy of transfusion medicine, especially in emergencies and …

Synthesis of bioactive hemoglobin-based oxygen carrier nanoparticles via metal-phenolic complexation

M Nadimifar, W Jin, C Coll-Satue, G Bor… - Biomaterials …, 2024 - Elsevier
The transfusion of donor red blood cells (RBCs) is seriously hampered by important
drawbacks that include limited availability and portability, the requirement of being stored in …

Hemoglobin nanoclusters-mediated regulation of KPNA4 in hypoxic tumor microenvironment enhances photodynamic therapy in hepatocellular carcinoma

Y Wang, N Li, L Qu, M Zhang, Z Li, X Li… - Journal of …, 2024 - Springer
Background Hepatocellular carcinoma (HCC) is a highly malignant tumor known for its
hypoxic environment, which contributes to resistance against the anticancer drug Sorafenib …

[HTML][HTML] Shedding Light on the Proteinaceous Envelope Protecting Luminescent Gold Nanoclusters: A Review

M Wacławska, W Dzwolak - Photochem, 2025 - mdpi.com
Atomically precise noble metal nanoclusters protected by ligands are broadly discussed in
the literature as a promising new class of materials with many interesting properties. Of …

Adsorption of hemoglobin onto gold nanoparticles: role of ligand coating on assembly formation and protein structure

K Lee, E Oh, MH Stewart, K Susumu, SA Díaz… - Journal of Nanoparticle …, 2025 - Springer
Understanding the interaction of hemoglobin (Hb) with various nanomaterials and
nanoparticles (NPs) is of considerable interest for the design of enhanced oxygen carriers …