Amyotrophic lateral sclerosis (ALS) is a fatal, multigenic, multifactorial, and non-cell
autonomous neurodegenerative disease characterized by upper and lower motor neuron …

Over the years, researchers have leveraged a host of different in vivo models in order to
dissect amyotrophic lateral sclerosis (ALS), a neurodegenerative/neuroinflammatory …

Highly ordered, straight amyloid fibrils readily lend themselves to structure determination
techniques and have therefore been extensively characterized. However, the less ordered …

Propolis, a compound produced by honeybees, has long been used in food and beverages
to improve health and prevent diseases. We previously reported that the ethanol extracts of …

Canine degenerative myelopathy (DM) is a human amyotrophic lateral sclerosis (ALS)-like
neurodegenerative disease. It is a unique, naturally occurring animal model of human ALS …

Canine degenerative myelopathy (CDM) is a late-onset fatal disorder associated with a point
mutation of the superoxide dismutase 1 (SOD1) gene (c. 118G> A). The purpose of this …

Amyotrophic lateral sclerosis is a fatal, multigenic, multifactorial neurodegenerative disease
characterized by upper and lower motor neuron loss. Animal models are essential for …

Canine degenerative myelopathy (DM) is a progressive neurodegenerative disorder, which
is commonly associated with c. 118G> A (p. E40K) missense mutation in the superoxide …

Amyloidogenic proteins form aggregates in cells, thereby leading to neurodegenerative
disorders, including Alzheimer's and prion's disease, amyotrophic lateral sclerosis (ALS) in …

Canine degenerative myelopathy (DM), a fatal neurodegenerative disease in dogs, shares
clinical and genetic features with amyotrophic lateral sclerosis, a human motor neuron …