Elastin in healthy and diseased lung

HJ Vindin, BGG Oliver, AS Weiss - Current opinion in biotechnology, 2022 - Elsevier
Highlights•Intact elastin is required for normal lung function.•High-resolution ECM
visualization assists in elastin imaging.•Improved lung imaging and modeling enhance ECM …

Increased Muc5AC and decreased ciliated cells in severe asthma partially restored by inhibition of IL-4Rα receptor

J Boomer, J Choi, A Alsup, MC McGregor… - American journal of …, 2024 - atsjournals.org
Rationale: The role of IL-13 on the airway epithelium in severe asthma leading to airway
remodeling remains poorly understood. Objectives: To study IL-13–induced airway …

Quantitative computed tomography imaging-based classification of cement dust-exposed subjects with an artificial neural network technique

T Kim, WJ Kim, CH Lee, KJ Chae, SH Bak… - Computers in Biology …, 2022 - Elsevier
Background and objective Cement dust exposure is likely to affect the structural and
functional alterations in segmental airways and parenchymal lungs. This study develops an …

A numerical study on airflow and particle transport characteristics of subjects with cement dust exposure

J Hwang, WJ Kim, KJ Chae, GY Jin… - Aerosol Science and …, 2024 - Taylor & Francis
Exposure to cement dust can cause respiratory problems and structural changes in
respiratory airways. Computed tomography (CT) has shown that the airways of individuals …

Computed tomography-based imaging biomarker identifies coal workers' pneumoconiosis

J Pyo, NK Chau, EK Park, S Choi - Frontiers in Physiology, 2023 - frontiersin.org
Rationale: The increase in the incidence and the diagnostic limitations of pneumoconiosis
have emerged as a public health concern. This study aimed to conduct a computed …

Inhalation dosimetry of nasally inhaled respiratory aerosols in the human respiratory tract with locally remodeled conducting lungs

XA Si, M Talaat, WC Su, J Xi - Inhalation Toxicology, 2021 - Taylor & Francis
Objective: Respiratory diseases are often accompanied by alterations to airway morphology.
However, inhalation dosimetry data in remodeled airways are scarce due to the challenges …

1D Network computational fluid dynamics for evaluating regional pressures in subjects with cement dust exposure

TM Tam, NQ Hung, X Cui, KJ Chae, S Kim, JS Yoo… - Journal of …, 2025 - Elsevier
Cement dust is a primary contributor to air pollution and is responsible for causing numerous
respiratory diseases. The impact of cement dust exposure on the respiratory health of …

Structural and functional alterations of subjects with cement dust exposure: a longitudinal quantitative computed tomography-based study

T Kim, M Lim, WJ Kim, TT Ho, CH Lee, KJ Chae… - Science of the Total …, 2022 - Elsevier
Cement dust exposure (CDE) can be a risk factor for pulmonary disease, causing changes
in segmental airways and parenchymal lungs. This study investigates longitudinal …

A comparative study of chest CT findings regarding the effects of regional dust exposure on patients with COPD living in urban areas and rural areas near cement …

J Kim, B Kim, SH Bak, YM Oh, WJ Kim - Respiratory Research, 2021 - Springer
Background The clinical and radiological presentation of chronic obstructive pulmonary
disease (COPD) is heterogenous depending on the characterized sources of inflammation …

Cement dust exposure alters secretory functions, biochemical profile and morphology of gastrointestinal tissues in rats exposed to cement dust

MW Owonikoko, OA Odukanmi, BO Emikpe… - Nigerian Journal of …, 2022 - ojshostng.com
Asides direct gastrointestinal exposure, inhalation route is another major xenobiotic
exposure pathway to the gastrointestinal tract via mucociliary escalator. This triphasic study …