Oxygen Activation and Energy Conservation by Cytochrome c Oxidase

M Wikström, K Krab, V Sharma - Chemical reviews, 2018 - ACS Publications
This review focuses on the type A cytochrome c oxidases (C c O), which are found in all
mitochondria and also in several aerobic bacteria. C c O catalyzes the respiratory reduction …

Recent advances in the theory and molecular simulation of biological electron transfer reactions

J Blumberger - Chemical reviews, 2015 - ACS Publications
1. INTRODUCTION AND OVERVIEW The transfer and transport of electrons through
biological matter is one of the key steps underlying cellular energy harvesting, storage, and …

Reaction Mechanism of Cytochrome c Oxidase

S Yoshikawa, A Shimada - Chemical reviews, 2015 - ACS Publications
Cytochrome c oxidase (CcO), the terminal oxidase of cell respiration, reduces molecular
oxygen (O2) in a reaction that is coupled with proton pumping. Since the discovery of this …

Spacer‐Engineered Ionic Channels in Covalent Organic Framework Membranes toward Ultrafast Proton Transport

B Shi, X Pang, B Lyu, H Wu, J Shen, J Guan… - Advanced …, 2023 - Wiley Online Library
Side‐chain engineering of covalent organic frameworks as advanced ion conductors is a
critical issue to be explored. Herein, ionic covalent organic framework membranes (iCOFMs) …

[HTML][HTML] Understanding mitochondrial complex I assembly in health and disease

M Mimaki, X Wang, M McKenzie, DR Thorburn… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Complex I (NADH: ubiquinone oxidoreductase) is the largest multimeric enzyme complex of
the mitochondrial respiratory chain, which is responsible for electron transport and the …

Proton-coupled electron transfer in cytochrome oxidase

VRI Kaila, MI Verkhovsky, M Wikström - Chemical reviews, 2010 - ACS Publications
Enzyme reactions that involve strong coupling between proton and electron transfer are of
fundamental importance in biology. This is particularly evident in the reactions of primary …

New perspectives on proton pumping in cellular respiration

M Wikstrom, V Sharma, VRI Kaila, JP Hosler… - Chemical …, 2015 - ACS Publications
Cellular respiration has a long research history at the interface between biology, chemistry,
and physics. Research in this field spans the entire range from fundamental mechanistic and …

[HTML][HTML] Cytochrome c oxidase deficiency

M Brischigliaro, M Zeviani - Biochimica et Biophysica Acta (BBA) …, 2021 - Elsevier
Cytochrome c oxidase (COX) deficiency is characterized by a high degree of genetic and
phenotypic heterogeneity, partly reflecting the extreme structural complexity, multiple post …

Polydopamine-modified graphene oxide nanocomposite membrane for proton exchange membrane fuel cell under anhydrous conditions

Y He, J Wang, H Zhang, T Zhang, B Zhang… - Journal of Materials …, 2014 - pubs.rsc.org
A new approach to the facile preparation of anhydrous proton exchange membrane (PEM)
enabled by artificial acid–base pairs is presented herein. Inspired by the bioadhesion of …

[HTML][HTML] Regulation of mitochondrial oxidative phosphorylation through cell signaling

M Hüttemann, I Lee, L Samavati, H Yu… - Biochimica et Biophysica …, 2007 - Elsevier
The mitochondrial oxidative phosphorylation (OxPhos) system plays a key role in energy
production, the generation of free radicals, and apoptosis. A lack of cellular energy …