Extracellular miRNAs: from biomarkers to mediators of physiology and disease
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
Overview of microRNA biogenesis, mechanisms of actions, and circulation
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
Mitochondrial mutations and mitoepigenetics: Focus on regulation of oxidative stress-induced responses in breast cancers
K Chen, P Lu, NM Beeraka, OA Sukocheva… - Seminars in cancer …, 2022 - Elsevier
Epigenetic regulation of mitochondrial DNA (mtDNA) is an emerging and fast-developing
field of research. Compared to regulation of nucler DNA, mechanisms of mtDNA epigenetic …
field of research. Compared to regulation of nucler DNA, mechanisms of mtDNA epigenetic …
Regulatory network of miRNA on its target: coordination between transcriptional and post-transcriptional regulation of gene expression
MicroRNAs (miRNAs) are a class of endogenous small noncoding RNAs that participate in a
majority of biological processes via regulating target gene expression. The post …
majority of biological processes via regulating target gene expression. The post …
Base-resolution mapping reveals distinct m1A methylome in nuclear-and mitochondrial-encoded transcripts
Gene expression can be post-transcriptionally regulated via dynamic and reversible RNA
modifications. N 1-methyladenosine (m 1 A) is a recently identified mRNA modification; …
modifications. N 1-methyladenosine (m 1 A) is a recently identified mRNA modification; …
[HTML][HTML] The host shapes the gut microbiota via fecal microRNA
The host gut microbiota varies across species and individuals but is relatively stable over
time within an individual. How the host selectively shapes the microbiota is largely unclear …
time within an individual. How the host selectively shapes the microbiota is largely unclear …
Mitochondrial biogenesis and clearance: a balancing act
C Ploumi, I Daskalaki, N Tavernarakis - The FEBS journal, 2017 - Wiley Online Library
Mitochondria are semi‐autonomous organelles of prokaryotic origin that are postulated to
have been acquired by eukaryotic cells through an early endosymbiotic event. Except for …
have been acquired by eukaryotic cells through an early endosymbiotic event. Except for …
microRNA therapeutics in cancer—an emerging concept
MY Shah, A Ferrajoli, AK Sood, G Lopez-Berestein… - …, 2016 - thelancet.com
MicroRNAs (miRNAs) are an evolutionarily conserved class of small, regulatory non-coding
RNAs that negatively regulate protein coding gene and other non-coding transcripts …
RNAs that negatively regulate protein coding gene and other non-coding transcripts …
Mitochondrial genome engineering: the revolution may not be CRISPR-Ized
In recent years mitochondrial DNA (mtDNA) has transitioned to greater prominence across
diverse areas of biology and medicine. The recognition of mitochondria as a major …
diverse areas of biology and medicine. The recognition of mitochondria as a major …
Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease
D Santovito, C Weber - Nature Reviews Cardiology, 2022 - nature.com
Research showing that microRNAs (miRNAs) are versatile regulators of gene expression
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …