The use of phytochemicals for purpose of cancer therapy has been accelerated due to
resistance of tumor cells to conventional chemotherapy drugs and therefore, monotherapy …

Simple Summary Cancer remains a major killer of the human population. Current cancer
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …

Epithelial cell adhesion molecule (EpCAM) is a type I transmembrane glycoprotein, which is
highly expressed on tumor cells. As EpCAM plays a crucial role in cell adhesion, survival …

CD44 is a cell surface glycoprotein, and its isoforms are produced by the alternative splicing
with the standard and variant exons. The CD44 variant exon-containing isoforms (CD44v) …

Liquid biopsies have emerged as a minimally invasive cancer detection and monitoring
method, which could identify cancer-related alterations in nucleosome or histone levels and …

Brain disorders represent a significant challenge in medical science due to the formidable
blood–brain barrier (BBB), which severely limits the penetration of conventional …

Over the past decade, the detection and analysis of liquid biopsy biomarkers such as
circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) have advanced …

The clinical presentation of renal cell cancer (RCC) is shifting towards incidental and early
detection, creating new challenges in RCC diagnosis. Overtreatment might be reduced with …

Precision medicine has driven a major change in the treatment of many forms of cancer. The
discovery that each patient is different and each tumor mass has its own characteristics has …

Circulating tumor cells (CTCs) are established as distinct cancer biomarkers for diagnosis,
as preclinical models, and therapeutic targets. Their use as preclinical models is limited …