[HTML][HTML] Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders

MMJ Van den Berg, J Krauskopf, JG Ramaekers… - Progress in …, 2020 - Elsevier
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …

A literature review of traumatic brain injury biomarkers

HS Ghaith, AA Nawar, MD Gabra… - Molecular …, 2022 - Springer
Research into TBI biomarkers has accelerated rapidly in the past decade owing to the
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …

A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers

MA Quail, M Smith, P Coupland, TD Otto, SR Harris… - BMC genomics, 2012 - Springer
Background Next generation sequencing (NGS) technology has revolutionized genomic and
genetic research. The pace of change in this area is rapid with three major new sequencing …

[HTML][HTML] Are circulating microRNAs peripheral biomarkers for Alzheimer's disease?

S Kumar, PH Reddy - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2016 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss, multiple cognitive abnormalities and intellectual impairments. Currently, there …

A rigorous method to enrich for exosomes from brain tissue

LJ Vella, BJ Scicluna, L Cheng… - Journal of …, 2017 - Taylor & Francis
Extracellular vesicles, including exosomes, are released by all cells, including those of the
nervous system. Capable of delivering lipid, protein and nucleic acids to both nearby and …

MicroRNA-128 governs neuronal excitability and motor behavior in mice

CL Tan, JL Plotkin, MT Venø, M Von Schimmelmann… - Science, 2013 - science.org
The control of motor behavior in animals and humans requires constant adaptation of
neuronal networks to signals of various types and strengths. We found that microRNA-128 …

miR-128-3p is a novel regulator of vascular smooth muscle cell phenotypic switch and vascular diseases

FM Farina, IF Hall, S Serio, S Zani, M Climent… - Circulation …, 2020 - Am Heart Assoc
Rationale: MicroRNAs (miRNAs, miRs) are small noncoding RNAs that modulate gene
expression by negatively regulating translation of target genes. Although the role of several …

MicroRNAs dysregulation and mitochondrial dysfunction in neurodegenerative diseases

M Catanesi, M d'Angelo, MG Tupone… - International Journal of …, 2020 - mdpi.com
Neurodegenerative diseases are debilitating and currently incurable conditions causing
severe cognitive and motor impairments, defined by the progressive deterioration of …

General principals of miRNA biogenesis and regulation in the brain

D O'carroll, A Schaefer - Neuropsychopharmacology, 2013 - nature.com
MicroRNAs (miRNAs) are small, noncoding RNAs that mediate posttranscriptional gene
suppression in a sequence-specific manner. The ability of a single miRNA species to target …

Peripheral whole blood microRNA alterations in major depression and bipolar disorder

E Maffioletti, A Cattaneo, G Rosso, G Maina… - Journal of affective …, 2016 - Elsevier
Major depression (MD) and bipolar disorder (BD) are severe and potentially life-threating
mood disorders whose etiology is to date not completely understood. MicroRNAs (miRNAs) …