[HTML][HTML] Fascin actin-bundling protein 1 in human cancer: promising biomarker or therapeutic target?

H Liu, Y Zhang, L Li, J Cao, Y Guo, Y Wu… - Molecular Therapy …, 2021 - cell.com
Fascin actin-bundling protein 1 (FSCN1) is a highly conserved actin-bundling protein that
cross links F-actin microfilaments into tight, parallel bundles. Elevated FSCN1 levels have …

[HTML][HTML] The role of fascin-1 in the pathogenesis, diagnosis and management of respiratory related cancers

N Zhang, Y Gao, Q Bian, Q Wang, Y Shi, Z Zhao… - Frontiers in …, 2022 - frontiersin.org
Human cancer statistics report that respiratory related cancers such as lung, laryngeal, oral
and nasopharyngeal cancers account for a large proportion of tumors, and tumor metastasis …

[HTML][HTML] Transcriptome analysis reveals the potential biological function of FSCN1 in HeLa cervical cancer cells

F Guo, Y Liu, Y Cheng, Q Zhang, W Quan, Y Wei… - PeerJ, 2022 - peerj.com
Fascin actin-bundling protein 1 (FSCN1), an actin-bundling protein associated with cell
migration and invasion, is highly expressed in various tumor tissues. FSCN1 has also been …

EPHA2 Promotes the Invasion and Migration of Human Tongue Squamous Cell Carcinoma Cal‐27 Cells by Enhancing AKT/mTOR Signaling Pathway

F Wang, H Zhang, Z Cheng - BioMed Research International, 2021 - Wiley Online Library
EPHA2 is a member of the ephrin receptor tyrosine kinase family and is closely related to the
malignant tumor progression. The effect of EPHA2 on OSCC is not clear. This study explored …

[HTML][HTML] An integrated approach for identification of a panel of candidate genes arbitrated for invasion and metastasis in oral squamous cell carcinoma

S Routray, R Kumar, KK Datta, VN Puttamallesh… - Scientific Reports, 2021 - nature.com
Oral squamous cell carcinoma (OSCC) is known for its aggressiveness associated with poor
prognosis. The molecular mechanisms underlying the invasion and metastasis are still …

Clinical significance of the TNF-α receptors, TNFRSF2 and TNFRSF9, on cell migration molecules Fascin-1 and Versican in acute leukemia

N El Kramani, NM Elsherbiny, AM El-Gayar… - Cytokine, 2018 - Elsevier
In human hematologic malignancies, some of the TNF receptor family members are up-
regulated and have the ability to evoke reactions favoring tumor progression. Moreover, cell …

Eukaryotic translation elongation factor 1δ, N-terminal propeptide of type I collagen and cancer-associated fibroblasts are prognostic markers of oral squamous cell …

CB Domingueti, DAQ Castilho, CE de Oliveira… - Oral surgery, oral …, 2020 - Elsevier
Objective Identifying markers that influence oral squamous cell carcinoma (OSCC)
prognosis is a fundamental strategy to improve the overall survival of patients. Markers such …

Prediction of lymph node metastasis in oral squamous cell carcinoma based on protein profile

B Yu, W Cao, C Zhang, R Xia, J Liu… - Expert Review of …, 2019 - Taylor & Francis
Objective: Lymph node metastasis leads to high mortality rates of oral squamous cell
carcinoma (OSCC). However, it is still controversial to define clinically negative neck (cN0) …

Evaluation of Fascin expression in oral erosive lichen planus and its relationship with potential of malignant transformation

F Shahsavari, M Emami… - Medical Journal of Tabriz …, 2024 - mj.tbzmed.ac.ir
Background. Fascin is a protein that is increased in many epithelial cancers, and this
increased expression is related to the more aggressive behavior and metastasis of many of …

[PDF][PDF] Immunohistochemical expression of fascin in oral epithelial dysplasia and oral squamous cell carcinoma

SC Natesan, BP Ramakrishnan, R Krishnapillai… - World J Dent, 2019 - wjoud.com
Aims: The present study aimed to evaluate and compare the expression of fascin in normal
oral mucosa (NOM) and oral epithelial dysplasia (OED) and to estimate the expression in …