Diagnosis early in life, sensitization, asthma endotypes, monitoring of disease and treatment
progression are key motivations for the exploration of biomarkers for allergic rhinitis and …

The definition of asthma has changed considerably in recent years, to the extent that asthma
is no longer considered a single disease but a heterogeneous disorder that includes several …

Chronic obstructive pulmonary disease (COPD) is a common heterogeneous respiratory
disease which is characterized by persistent and incompletely reversible airflow limitation …

Background Bronchial asthma is a heterogeneous disease characterized by three cardinal
features: chronic inflammation, variable airflow obstruction, and airway …

Background Asthma is heterogeneous disease with different phenotypes, endotypes and
severities. Definition of these subgroups requires the identification of biomarkers in …

Asthma is a complex chronic inflammatory disease of multifactorial etiology. International
guidelines increasingly recognize that a standard “one size fits all” approach is no longer an …

Introduction: We argue that asthma be considered a syndrome caused by multiple
inflammatory pathogenic processes. Bronchial hyperresponsiveness, reversible airflow …

Asthma is a common condition caused by immune and respiratory dysfunction, and it is often
linked to allergy. A systems perspective may prove helpful in unravelling the complexity of …

Introduction: Lung cancer and related diseases have been one of the most common causes
of deaths worldwide. Genomic-based biomarkers may hardly reflect the underlying dynamic …

Although different phenotypes of severe asthma can be identified, all are characterized by
common symptoms. Due to their heterogeneity, they exhibit differences in pathogenesis …