Intervertebral disc (IVD) degeneration is a multifactorial pathological process associated
with low back pain, the leading cause of years lived in disability worldwide. Key …

Magnetic resonance imaging (MRI) uses a large magnetic field and radio waves to generate
images of tissues in the body. Conventional MRI techniques have been developed to image …

Abstract Purpose of Review The endplates form the interface between the rigid vertebral
bodies and compliant intervertebral discs. Proper endplate function involves a balance …

Objective Intradiscal biologic therapy is a promising strategy for managing intervertebral disc
degeneration. However, these therapies require a rich nutrient supply, which may be limited …

The intervertebral disc is the largest avascular structure in the body, and cells within the disc
rely on diffusive transport via vasculature located within the vertebral endplate to receive …

Objectives To evaluate the performance of 3D T1w spoiled gradient-echo (T1SGRE) and
ultra-short echo time (UTE) MRI sequences for the detection and assessment of vertebral …

Back and neck pain have become a primary cause of disability and healthcare spending
globally. While the causes of back pain are multifactorial, intervertebral disc degeneration is …

The cartilaginous endplates (CEP) are key components of the intervertebral disc (IVD)
necessary for sustaining the nutrition of the disc while distributing mechanical loads and …

Background Histopathological analysis of intervertebral disc (IVD) tissues is a critical
domain of back pain research. Identification, description, and classification of attributes that …

Low back pain (LBP) is one of the leading causes of disability worldwide, with a significant
socioeconomic burden on healthcare systems. It is mainly caused by degenerative disc …