The innate immune system utilizes many approaches for defense against invading
microorganisms, including complement-mediated lysis, engulfment, formation of neutrophil …

Parkinson's disease is a neurodegenerative disorder characterized by progressive loss of
dopaminergic neurons of the substantia nigra pars compacta with a reduction of dopamine …

Amyloid-β peptide (Aβ) fibrilization and deposition as β-amyloid are hallmarks of Alzheimer's
disease (AD) pathology. We recently reported Aβ is an innate immune protein that protects …

Plasmacytoid dendritic cells (pDCs) sense viral and microbial DNA through endosomal Toll-
like receptors to produce type 1 interferons. pDCs do not normally respond to self-DNA, but …

Dendritic cell (DC) responses to extracellular self-DNA and self-RNA are prevented by the
endosomal seclusion of nucleic acid–recognizing Toll-like receptors (TLRs). In psoriasis …

Antimicrobial peptides (AMPs) are multi-functional peptides whose fundamental biological
role in vivo has been proposed to be the elimination of pathogenic microorganisms …

Antimicrobial peptides and their precursor molecules form a central part of human and
mammalian innate immunity. The underlying genes have been thoroughly investigated and …

Antimicrobial peptides (AMPs) are produced by neutrophils, monocytes, and macrophages,
as well as epithelial cells, and are an essential component of innate immunity system …

The cathelicidin peptides comprise one of several families of antimicrobial peptides that are
found in neutrophils and epithelia as components of the early host defenses of mammals …

Host defence peptides are found in all classes of life and are a fundamental component of
the innate immune response. Initially it was believed that their sole role in innate immunity …