Advanced therapy medicinal products: a guide for bone marrow-derived MSC application in bone and cartilage tissue engineering

D Confalonieri, A Schwab, H Walles… - Tissue Engineering Part …, 2018 - liebertpub.com
Millions of people worldwide suffer from trauma-or age-related orthopedic diseases such as
osteoarthritis, osteoporosis, or cancer. Tissue Engineering (TE) and Regenerative Medicine …

Defining the balance between regeneration and pathological ossification in skeletal muscle following traumatic injury

OG Davies, Y Liu, DJ Player, NRW Martin… - Frontiers in …, 2017 - frontiersin.org
Heterotopic ossification (HO) is characterized by the formation of bone at atypical sites. This
type of ectopic bone formation is most prominent in skeletal muscle, most frequently …

Novel Biomaterial-Binding/Osteogenic Bi-Functional Peptide Binds to Silk Fibroin Membranes to Effectively Induce Osteogenesis In Vitro and In Vivo

R Lyu, Y Chen, Y Shuai, J Wang, L Lu… - … Applied Materials & …, 2023 - ACS Publications
Peptides can introduce new functions to biomaterials but their immobilization usually relies
on inefficient physical adsorption or tedious chemical conjugation. Using the Bombyx mori …

Osteoinductive and anti-inflammatory properties of chitosan-based scaffolds for bone regeneration

I Fasolino, MG Raucci, A Soriente, C Demitri… - Materials Science and …, 2019 - Elsevier
Current bone implants based on new biomaterials may cause a foreign body reaction (FBR)
around the implant itself thus prolonging the healing time following bone fractures. In this …

Mesenchymal stem cells alleviate experimental immune-mediated liver injury via chitinase 3-like protein 1-mediated T cell suppression

Q Liu, X Chen, C Liu, L Pan, X Kang, Y Li, C Du… - Cell Death & …, 2021 - nature.com
Liver diseases with different pathogenesis share common pathways of immune-mediated
injury. Chitinase-3-like protein 1 (CHI3L1) was induced in both acute and chronic liver …

Interleukin‐20 differentially regulates bone mesenchymal stem cell activities in RANKL‐induced osteoclastogenesis through the OPG/RANKL/RANK axis and the NF …

B Meng, D Wu, Y Cheng, P Huang, Y Liu… - Scandinavian …, 2020 - Wiley Online Library
The immune and skeletal systems share common mechanisms, and the crosstalk between
the two has been termed osteoimmunology. Osteoimmunology mainly focuses on diseases …

Potential role of long non‐coding RNA in osteogenic differentiation of human periodontal ligament stem cells

Q Qu, F Fang, B Wu, Y Hu, M Chen… - Journal of …, 2016 - Wiley Online Library
Background: Long non‐coding RNAs (lncRNAs) are emerging as important regulators of
eukaryotic gene expression and have been shown to regulate various modular components …

Bone marrow-derived cells and their conditioned medium induce microvascular repair in uremic rats by stimulation of endogenous repair mechanisms

L Golle, HU Gerth, K Beul, B Heitplatz, P Barth… - Scientific reports, 2017 - nature.com
The reduced number of circulating stem/progenitor cells that is found in chronic kidney
disease (CKD) patients may contribute to impaired angiogenic repair and decreased …

Interleukin‐20 acts as a promotor of osteoclastogenesis and orthodontic tooth movement

Y Liu, Y Ai, X Sun, B Meng, X Chen, D Wu… - Stem Cells …, 2021 - Wiley Online Library
Objectives. Bones constitute organs that are engaged in constant self‐remodelling.
Osteoblast and osteoclast homeostasis during remodelling contribute to overall skeletal …

Interleukin-19 promotes bone resorption by suppressing osteoprotegerin expression in BMSCs in a lipopolysaccharide-induced bone loss mouse model

Z Dai, Y Chen, E He, H Wang, W Guo… - Bone & Joint …, 2023 - boneandjoint.org.uk
Aims Osteoporosis is characterized by decreased trabecular bone volume, and
microarchitectural deterioration in the medullary cavity. Interleukin-19 (IL-19), a member of …