Hypertension, a moving target in COVID-19: current views and perspectives

C Savoia, M Volpe, R Kreutz - Circulation Research, 2021 - Am Heart Assoc
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) associates with a considerable high rate of mortality and …

Toward precision medicine: circadian rhythm of blood pressure and chronotherapy for hypertension-2021 NHLBI workshop report

ML Gumz, D Shimbo, M Abdalla, RC Balijepalli… - …, 2023 - Am Heart Assoc
Healthy individuals exhibit blood pressure variation over a 24-hour period with higher blood
pressure during wakefulness and lower blood pressure during sleep. Loss or disruption of …

Metabolic rewiring and communication: an integrative view of kidney proximal tubule function

M Chrysopoulou, MM Rinschen - Annual Review of Physiology, 2024 - annualreviews.org
The kidney proximal tubule is a key organ for human metabolism. The kidney responds to
stress with altered metabolite transformation and perturbed metabolic pathways, an ultimate …

The causal associations of circulating amino acids with blood pressure: a Mendelian randomization study

C Lin, Z Sun, Z Mei, H Zeng, M Zhao, J Hu, M Xia… - BMC medicine, 2022 - Springer
Background Circulating levels of amino acids were associated with blood pressure (BP) in
observational studies. However, the causation of such associations has been hypothesized …

The damaging duo: Obesity and excess dietary salt contribute to hypertension and cardiovascular disease

JC Watso, IS Fancher, DH Gomez… - Obesity …, 2023 - Wiley Online Library
Hypertension is a primary risk factor for cardiovascular disease. Cardiovascular disease is
the leading cause of death among adults worldwide. In this review, we focus on two of the …

[HTML][HTML] Innate immune cells and hypertension: neutrophils and neutrophil extracellular traps (NETs)

CG McCarthy, P Saha, RM Golonka… - Comprehensive …, 2021 - ncbi.nlm.nih.gov
Uncontrolled immune system activation amplifies end-organ injury in hypertension.
Nonetheless, the exact mechanisms initiating this exacerbated inflammatory response …

Prospects for leveraging the microbiota as medicine for hypertension

DJ Durgan, J Zubcevic, M Vijay-Kumar, T Yang… - …, 2024 - Am Heart Assoc
Prospects for Leveraging the Microbiota as Medicine for Hypertension | Hypertension Science
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Therapeutic significance of microRNA-mediated regulation of PARP-1 in SARS-CoV-2 infection

S Dash, C Dash, J Pandhare - Non-coding RNA, 2021 - mdpi.com
The COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2 (2019-nCoV) has
devastated global healthcare and economies. Despite the stabilization of infectivity rates in …

Repurposing a drug targeting inflammatory bowel disease for lowering hypertension

X Mei, B Mell, I Manandhar, S Aryal… - Journal of the …, 2022 - Am Heart Assoc
Background The gut and gut microbiota, which were previously neglected in blood pressure
regulation, are becoming increasingly recognized as factors contributing to hypertension …

A hierarchical approach to removal of unwanted variation for large-scale metabolomics data

T Kim, O Tang, ST Vernon, KA Kott, YC Koay… - Nature …, 2021 - nature.com
Liquid chromatography-mass spectrometry-based metabolomics studies are increasingly
applied to large population cohorts, which run for several weeks or even years in data …