[HTML][HTML] Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics

V Bourganis, O Kammona, A Alexopoulos… - European Journal of …, 2018 - Elsevier
Central nervous system (CNS) disorders (eg, multiple sclerosis, Alzheimer's disease, etc.)
represent a growing public health issue, primarily due to the increased life expectancy and …

[HTML][HTML] Pulmonary delivery of biological drugs

W Liang, HW Pan, D Vllasaliu, JKW Lam - Pharmaceutics, 2020 - mdpi.com
In the last decade, biological drugs have rapidly proliferated and have now become an
important therapeutic modality. This is because of their high potency, high specificity and …

Chitosan nanoparticles: Preparation, size evolution and stability

A Rampino, M Borgogna, P Blasi, B Bellich… - International journal of …, 2013 - Elsevier
Purpose Characterisation of chitosan-tripolyphosphate nanoparticles is presented with the
aim of correlating particle shape and morphology, size distribution, surface chemistry, and …

[HTML][HTML] Strategic approaches to improvise peptide drugs as next generation therapeutics

P Barman, S Joshi, S Sharma, S Preet… - International journal of …, 2023 - Springer
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

[HTML][HTML] The emergence of peptides in the pharmaceutical business: From exploration to exploitation

T Uhlig, T Kyprianou, FG Martinelli, CA Oppici… - EuPA open …, 2014 - Elsevier
This minireview touches upon the challenges and opportunities peptides experience on the
track to become an approved pharmaceutical. Peptide attributes originally considered …

[HTML][HTML] Biomedical applications of quaternized chitosan

K Pathak, SK Misra, A Sehgal, S Singh, S Bungau… - Polymers, 2021 - mdpi.com
The natural polymer chitosan is the second most abundant biopolymer on earth after chitin
and has been extensively explored for preparation of versatile drug delivery systems. The …

Nanomedicine in the management of microbial infection–overview and perspectives

X Zhu, AF Radovic-Moreno, J Wu, R Langer, J Shi - Nano today, 2014 - Elsevier
For more than 2 billion years, microbes have reigned on our planet, evolving or outlasting
many obstacles they have encountered. In the 20th century, this trend took a dramatic turn …

Recent advances on chitosan as an adjuvant for vaccine delivery

I Dmour, N Islam - International Journal of Biological Macromolecules, 2022 - Elsevier
Chitosan (CS) is a natural polymer derived from chitin that has wide applications in drugs,
vaccines, and antigen delivery. The distinctive mucoadhesive, biocompatibility …

Polymeric nanoparticle drug delivery technologies for oral delivery applications

EM Pridgen, F Alexis, OC Farokhzad - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Many therapeutics are limited to parenteral administration. Oral administration
is a desirable alternative because of the convenience and increased compliance by …

Vaccines, adjuvants and key factors for mucosal immune response

VA Correa, AI Portilho, E De Gaspari - Immunology, 2022 - Wiley Online Library
Vaccines are the most effective tool to control infectious diseases, which provoke significant
morbidity and mortality rates. Most vaccines are administered through the parenteral route …