The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta‐analysis

AT Page, RM Clifford, K Potter… - British journal of …, 2016 - Wiley Online Library
Aims Deprescribing is a suggested intervention to reverse the potential iatrogenic harms of
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …

Fall-risk-increasing drugs: a systematic review and meta-analysis: I. Cardiovascular drugs

M de Vries, LJ Seppala, JG Daams… - Journal of the American …, 2018 - Elsevier
Background and objective Use of certain medications is recognized as a major and
modifiable risk factor for falls. Although the literature on psychotropic drugs is compelling …

Medication-related falls in the elderly: causative factors and preventive strategies

AR Huang, L Mallet, CM Rochefort, T Eguale… - Drugs & aging, 2012 - Springer
People are living to older age. Falls constitute a leading cause of injuries, hospitalization
and deaths among the elderly. Older people fall more often for a variety of reasons …

Drug-related falls in older patients: implicated drugs, consequences, and possible prevention strategies

MR De Jong, M Van der Elst… - … advances in drug …, 2013 - journals.sagepub.com
Falls are the leading cause of injuries among older adults, aged 65 years and older.
Furthermore, falls are an increasing public health problem because of ageing populations …

Medication withdrawal trials in people aged 65 years and older: a systematic review

S Iyer, V Naganathan, AJ McLachlan, DG Le Conteur - Drugs & aging, 2008 - Springer
The objective of this review was to assess the benefits and risks of medication withdrawal in
older people as documented in published trials of medication withdrawal. This was done by …

Use of fall risk–increasing drugs around a fall‐related injury in older adults: A systematic review

LA Hart, EA Phelan, JY Yi, ZA Marcum… - Journal of the …, 2020 - Wiley Online Library
OBJECTIVES To examine:(1) prevalence of fall risk–increasing drug (FRID) use among
older adults with a fall‐related injury,(2) which FRIDs were most frequently prescribed,(3) …

Fall risk-increasing drugs and falls: a cross-sectional study among elderly patients in primary care

V Milos, Å Bondesson, M Magnusson, U Jakobsson… - BMC geriatrics, 2014 - Springer
Background Falls are the most common cause of injuries and hospital admissions in the
elderly. The Swedish National Board of Health and Welfare has created a list of drugs …

Polypharmacy and falls in older people: Balancing evidence-based medicine against falls risk

A Zia, SB Kamaruzzaman, MP Tan - Postgraduate medicine, 2015 - Taylor & Francis
The term polypharmacy has negative connotations due to its association with adverse drug
reactions and falls. This spectrum of adverse events widens when polypharmacy occurs …

Associations between drug burden index and falls in older people in residential aged care

NM Wilson, SN Hilmer, LM March… - Journal of the …, 2011 - Wiley Online Library
OBJECTIVES: To evaluate the association between the Drug Burden Index (DBI), a measure
of a person's total exposure to anticholinergic and sedative medications that includes …

Reducing the risk of adverse drug events in older adults

RW Pretorius, G Gataric, SK Swedlund… - American family …, 2013 - aafp.org
Adverse drug events occur in 15 percent or more of older patients presenting to offices,
hospitals, and extended care facilities. These events are potentially preventable up to 50 …