Autophagy in age‐related macular degeneration: a regulatory mechanism of oxidative stress

ZY Zhang, XL Bao, YY Cong, B Fan… - Oxidative medicine and …, 2020 - Wiley Online Library
Age‐related macular degeneration (AMD) is a leading cause of severe visual loss and
irreversible blindness in the elderly population worldwide. Retinal pigment epithelial (RPE) …

Mitochondria as potential targets and initiators of the blue light hazard to the retina

JX Tao, WC Zhou, XG Zhu - Oxidative medicine and cellular …, 2019 - Wiley Online Library
Commercially available white light‐emitting diodes (LEDs) have an intense emission in the
range of blue light, which has raised a range of public concerns about their potential risks as …

An annexin V-FITC—propidium iodide-based method for detecting apoptosis in a non-small cell lung cancer cell line

R Kumar, A Saneja, AK Panda - Lung Cancer: Methods and Protocols, 2021 - Springer
Annexin V and propidium iodide staining is widely used for determining the cellular death
through apoptosis. In the presence of Ca 2+ ions, annexin V has a strong binding affinity for …

Protective effect of melatonin against oxidative stress‐induced apoptosis and enhanced autophagy in human retinal pigment epithelium cells

CC Chang, TY Huang, HY Chen… - Oxidative Medicine …, 2018 - Wiley Online Library
Age‐related macular degeneration (AMD) affects the retinal macula and results in loss of
vision, and AMD is the primary cause of blindness and severe visual impairment among …

Homocysteine and cytosolic GSH depletion induce apoptosis and oxidative toxicity through cytosolic calcium overload in the hippocampus of aged mice: involvement …

IS Övey, M Naziroğlu - Neuroscience, 2015 - Elsevier
Oxidative stress and apoptosis were induced in neuronal cultures by inhibition of glutathione
(GSH) biosynthesis with d, l-buthionine-S, R-sulfoximine (BSO). Transient receptor potential …

[HTML][HTML] Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment

J Li, Z Yang, Y Li, J Xia, D Li, H Li, M Ren, Y Liao… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Osteosarcoma is the most common primary bone tumor in children and adolescents.
Although combined therapy including surgery and multi-agent chemotherapy have resulted …

[HTML][HTML] Investigation of the effects of distance from sources on apoptosis, oxidative stress and cytosolic calcium accumulation via TRPV1 channels induced by mobile …

B Çiğ, M Nazıroğlu - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2015 - Elsevier
TRPV1 is a Ca 2+ permeable channel and gated by noxious heat, oxidative stress and
capsaicin (CAP). Some reports have indicated that non-ionized electromagnetic radiation …

[HTML][HTML] Blue light pollution causes retinal damage and degeneration by inducing ferroptosis

X Li, S Zhu, F Qi - Journal of Photochemistry and Photobiology B: Biology, 2023 - Elsevier
With the development of technology and electronic products, the problem of light pollution is
becoming more and more serious. Blue light, the most energetic light in visible light, is the …

Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment

S Mehrzadi, K Hemati, RJ Reiter… - Expert opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction: Age-related Macular Degeneration (AMD), a retinal
neurodegenerative disease is the most common cause of blindness among the elderly in …

[HTML][HTML] Inhibition of oxidative stress-induced epithelial-mesenchymal transition in retinal pigment epithelial cells of age-related macular degeneration model by …

YC Yang, Y Chien, AA Yarmishyn, LY Lim… - Journal of Advanced …, 2024 - Elsevier
Introduction Epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE)
cells is related to the pathogenesis of various retinopathies including age-related macular …