Cannabinoids and the expanded endocannabinoid system in neurological disorders

L Cristino, T Bisogno, V Di Marzo - Nature Reviews Neurology, 2020 - nature.com
Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …

Protective Effects of (E)-β-Caryophyllene (BCP) in Chronic Inflammation

R Scandiffio, F Geddo, E Cottone, G Querio… - Nutrients, 2020 - mdpi.com
(E)-β-caryophyllene (BCP) is a bicyclic sesquiterpene widely distributed in the plant
kingdom, where it contributes a unique aroma to essential oils and has a pivotal role in the …

Hydroxytyrosol protects from aging process via AMPK and autophagy; a review of its effects on cancer, metabolic syndrome, osteoporosis, immune-mediated and …

RM De Pablos, AM Espinosa-Oliva… - Pharmacological …, 2019 - Elsevier
Aging is a complex process. It is considered a risk factor for several diseases such as
cancer, neurodegenerative diseases, cardiovascular diseases, and diabetes, most of which …

Glial cell-mediated neuroinflammation in Alzheimer's disease

NF Al-Ghraiybah, J Wang, AE Alkhalifa… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder; it is the most
common cause of dementia and has no treatment. It is characterized by two pathological …

[HTML][HTML] The impact of phyto-and endo-cannabinoids on central nervous system diseases: A review

SS Zhang, NN Zhang, TT Guo, LY Sheen, CT Ho… - Journal of Traditional …, 2023 - Elsevier
Background and aim Cannabis sativa L. is a medicinal plant with a long history. Phyto-
cannabinoids are a class of compounds from C. sativa L. with varieties of structures …

Cannabis and its derivatives for the use of motor symptoms in Parkinson's disease: A systematic review and meta-analysis

SJ Thanabalasingam, B Ranjith… - Therapeutic …, 2021 - journals.sagepub.com
Background: Recent changes to the legal status of cannabis across various countries have
renewed interest in exploring its use in Parkinson's disease (PD). The use of cannabinoids …

Effects of Nabilone on sleep outcomes in patients with Parkinson's disease: A post‐hoc analysis of NMS‐Nab study

M Peball, K Seppi, F Krismer, HG Knaus… - Movement disorders …, 2022 - Wiley Online Library
Background The synthetic tetrahydrocannabinol analogue nabilone improved overall non‐
motor symptom (NMS) burden in Parkinson's disease (PD) patients in comparison to …

Cannabidiol and Cannabinoid Compounds as Potential Strategies for Treating Parkinson's Disease and l-DOPA-Induced Dyskinesia

NCF Junior, M dos- Santos-Pereira, FS Guimarães… - Neurotoxicity …, 2020 - Springer
Parkinson's disease (PD) and l-DOPA-induced dyskinesia (LID) are motor disorders with
significant impact on the patient's quality of life. Unfortunately, pharmacological treatments …

The endocannabinoid system and related lipids as potential targets for the treatment of migraine‐related pain

R Greco, C Demartini, AM Zanaboni… - … : The Journal of …, 2022 - Wiley Online Library
Background Migraine is a complex and highly disabling neurological disease whose
treatment remains challenging in many patients, even after the recent advent of the first …

Possible therapeutic applications of cannabis in the neuropsychopharmacology field

J Fernández-Ruiz, I Galve-Roperh, O Sagredo… - European …, 2020 - Elsevier
Cannabis use induces a plethora of actions on the CNS via its active chemical ingredients,
the so-called phytocannabinoids. These compounds have been frequently associated with …