Why animal experiments are still indispensable in bone research: A statement by the European Calcified Tissue Society

M Stein, F Elefteriou, B Busse… - Journal of Bone and …, 2023 - academic.oup.com
Major achievements in bone research have always relied on animal models and in vitro
systems derived from patient and animal material. However, the use of animals in research …

Gas Therapy: generating, delivery, and biomedical applications

P Ghaffari‐Bohlouli, H Jafari, OV Okoro… - Small …, 2024 - Wiley Online Library
Abstract Oxygen (O2), nitric oxide (NO), carbon monoxide (CO), hydrogen sulfide (H2S), and
hydrogen (H2) with direct effects, and carbon dioxide (CO2) with complementary effects on …

Development of a biomimetic arch-like 3D bioprinted construct for cartilage regeneration using gelatin methacryloyl and silk fibroin-gelatin bioinks

J Chakraborty, J Fernández-Pérez… - …, 2023 - iopscience.iop.org
In recent years, engineering biomimetic cellular microenvironments have been a top priority
for regenerative medicine. Collagen II, which is arranged in arches, forms the predominant …

[HTML][HTML] A bilayer collagen scaffold with bevacizumab stabilizes chondrogenesis and promotes osteochondral regeneration

X Zheng, N Li, Y Xu, C Zhang, Y Ouyang, D Meng - Materials & Design, 2022 - Elsevier
Stem cell-based tissue engineering represents a promising therapeutic for osteochondral
restoration. A bilayer scaffold with an appropriate niche can simultaneously induce stem …

[HTML][HTML] Craniofacial chondrogenesis in organoids from human stem cell-derived neural crest cells

L Foltz, N Avabhrath, JM Lanchy, T Levy, A Possemato… - Iscience, 2024 - cell.com
Knowledge of cell signaling pathways that drive human neural crest differentiation into
craniofacial chondrocytes is incomplete, yet essential for using stem cells to regenerate …

The Role of Immunocyte Infiltration Regulatory Network Based on hdWGCNA and Single-Cell Bioinformatics Analysis in Intervertebral Disc Degeneration

T Shao, Q Gao, W Tang, Y Ma, J Gu, Z Yu - Inflammation, 2024 - Springer
Immune infiltration plays a crucial role in intervertebral disc degeneration (IDD). In this study,
we explored the immune microenvironment of IDD through single-cell bioinformatics …

[HTML][HTML] IBM Watson AI-enhanced search tool identifies novel candidate genes and provides insight into potential pathomechanisms of traumatic heterotopic …

N Foster, FM Wood, M Fear, N Pavlos, E Raby… - Burns Open, 2023 - Elsevier
Background Traumatic heterotopic ossification (tHO) is the pathological formation of ectopic
bone in soft tissues that can occur following injury to the skin, nervous system, or direct …

[PDF][PDF] Burns Open

N Foster, FM Wood, M Fear, N Pavlos, E Raby… - researchgate.net
Background: Traumatic heterotopic ossification (tHO) is the pathological formation of ectopic
bone in soft tissues that can occur following injury to the skin, nervous system, or direct …