Introduction. Sickle cell disease (SCD) is a chronic disease characterized by debilitating
bone pains which commonly necessitate the use of analgesic drugs including opioids and …

Introduction: opioids are a mainstay in sickle cell disease (SCD) pain care. Opioids are
known to cause physical and/or psychological dependence. Increasingly, a significant …

The incidences of drug adulteration and drug resistance have been a major problem facing
mankind in recent years. Low and medium-income countries like Nigeria are most affected …

Background: Pentazocine is a synthetic opioid analgesic with mixed receptor activities. It
acts as a partial agonist at the µ-receptor as well as being a kappa agonist. Its analgesic …

Painful crisis is the commonest and most distressing clinical manifestation of sickle cell
anaemia (SCA), thus prompt and adequate analgesia should be provided to ameliorate the …

Background: Moderate to severe pain is common in the intensive care unit (ICU). There are
various sources of pain in the ICU ranging from trauma-related pain, acute post-operative …

Background: Opioids are a group of potent analgesic with mixed receptor activities. Pain
related symptom accounts for the main reason for substance dependence among sickle cell …

Recently, Pentazocine and alcohol have become one of the drugs abused in the developing
countries. However, there is the dearth of information on the effects of these substances on …

Introduction. Sickle cell disease (SCD) is a chronic disease characterized by debilitating
bone pains which commonly necessitate the use of analgesic drugs including opioids and …

Pentazocine is one of the commonly prescribed narcotic analgesics for acute pain
management such as post-operative or post-traumatic pain in developing countries. It has a …