More than 80 years ago, the first Polycomb-related phenotype was identified in Drosophila
melanogaster. Later, a group of diverse genes collectively called Polycomb group (PcG) …

Cancer arises from a multitude of disorders resulting in loss of differentiation and a stem cell-
like phenotype characterized by uncontrolled growth. Polycomb Group (PcG) proteins are …

BACKGROUND Multicellular organisms depend on the precise orchestration of gene
expression to direct embryonic development and to maintain tissue homeostasis through …

Polycomb Group (PcG) proteins are transcriptional repressors that epigenetically modify
chromatin and participate in the establishment and maintenance of cell fates. These proteins …

MicroRNAs (miR) show characteristic expression signatures in various cancers and can
profoundly affect cancer cell behavior. We carried out miR expression profiling of human …

The polycomb group protein B lymphoma Mo-MLV insertion region 1 homolog (Bmi-1) is
dysregulated in various cancers, and its upregulation strongly correlates with an invasive …

Background B-lymphoma Moloney murine leukemia virus insertion region-1 (Bmi-1) acts as
an oncogene in various tumors, and its overexpression correlates with a poor outcome in …

Background Chromobox protein homolog 7 (CBX7), a member of the polycomb group (PcG)
family of proteins, is involved in the regulation of cell proliferation and cancer progression …

Purpose: The circadian clock gene Bmal1 is involved in cancer cell proliferation and DNA
damage sensitivity. The aim of this study was to explore the effect of Bmal1 on oxaliplatin …

The chromatin-associated Polycomb Group (PcG) proteins were first identified in genetic
screens for homeotic transformations in Drosophila melanogaster. In addition to body …