PEG-based thermosensitive and biodegradable hydrogels

J Shi, L Yu, J Ding - Acta biomaterialia, 2021 - Elsevier
Injectable thermosensitive hydrogels are free-flowing polymer solutions at low or room
temperature, making them easy to encapsulate the therapeutic payload or cells via simply …

Injectable hydrogels for cartilage and bone tissue engineering

M Liu, X Zeng, C Ma, H Yi, Z Ali, X Mou, S Li, Y Deng… - Bone research, 2017 - nature.com
Tissue engineering has become a promising strategy for repairing damaged cartilage and
bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels …

Polymers exhibiting lower critical solution temperatures as a route to thermoreversible gelators for healthcare

MT Cook, P Haddow, SB Kirton… - Advanced Functional …, 2021 - Wiley Online Library
The ability to trigger changes to material properties with external stimuli, so‐called “smart”
behavior, has enabled novel technologies for a wide range of healthcare applications …

Thermosensitive hydrogels as scaffolds for cartilage tissue engineering

Y Zhang, J Yu, K Ren, J Zuo, J Ding… - Biomacromolecules, 2019 - ACS Publications
Articular cartilage defects, caused by trauma, osteoarthritis, or other diseases, always lead to
severe joint pain and joint dysfunction. Without access to progenitor cells and the supply of …

Biodegradable thermoresponsive polymers: Applications in drug delivery and tissue engineering

KJ Hogan, AG Mikos - Polymer, 2020 - Elsevier
Thermoresponsive polymers have been investigated for a variety of clinical applications
which make use of in situ gelation at physiological temperatures. However, for biomedical …

In situ gelling pH-and temperature-sensitive biodegradable block copolymer hydrogels for drug delivery

NK Singh, DS Lee - Journal of Controlled Release, 2014 - Elsevier
Stimuli-sensitive injectable polymeric hydrogels have been extensively investigated during
the past decade as bioactive agent delivery vehicles and for tissue engineering applications …

Injectable glycopolypeptide hydrogels as biomimetic scaffolds for cartilage tissue engineering

K Ren, C He, C Xiao, G Li, X Chen - Biomaterials, 2015 - Elsevier
Glycopolypeptides are an emerging class of bioinspired polymers that mimic naturally
occurring glycopeptides or glycoproteins, and therefore are expected to exhibit great …

An injectable hydrogel formed by in situ cross-linking of glycol chitosan and multi-benzaldehyde functionalized PEG analogues for cartilage tissue engineering

L Cao, B Cao, C Lu, G Wang, L Yu… - Journal of materials …, 2015 - pubs.rsc.org
In this study, a multi-benzaldehyde functionalized poly (ethylene glycol) analogue, poly
(ethylene oxide-co-glycidol)-CHO (poly (EO-co-Gly)-CHO), was designed and synthesized …

Human adipose stem cells: from bench to bedside

F De Francesco, G Ricci, F D'Andrea… - … Engineering Part B …, 2015 - liebertpub.com
Stem cell-based therapies for repair and regeneration of different tissues are becoming
more important in the treatment of several diseases. Adult stem cells currently symbolize the …

A comprehensive review on polymeric hydrogel and its composite: Matrices of choice for bone and cartilage tissue engineering

HDN Tran, KD Park, YC Ching, C Huynh… - Journal of Industrial and …, 2020 - Elsevier
The need of tissue and organ for transplantation to repair or replace damaged tissues is
significantly higher than the availability of donated organs. Tissue engineering that develops …