[HTML][HTML] Global colorectal cancer burden in 2020 and projections to 2040
As the third most common malignancy and the second most deadly cancer, colorectal
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies
NN Keum, E Giovannucci - Nature reviews Gastroenterology & …, 2019 - nature.com
Globally, colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the
second leading cause of cancer death. Arising through three major pathways, including …
second leading cause of cancer death. Arising through three major pathways, including …
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
Colorectal cancer (CRC) is a leading cause of mortality worldwide. We conducted a genome-
wide association study meta-analysis of 100,204 CRC cases and 154,587 controls of …
wide association study meta-analysis of 100,204 CRC cases and 154,587 controls of …
Colorectal cancer
E Dekker, PJ Tanis, JLA Vleugels, PM Kasi… - The Lancet, 2019 - thelancet.com
Several decades ago, colorectal cancer was infrequently diagnosed. Nowadays, it is the
world's fourth most deadly cancer with almost 900 000 deaths annually. Besides an ageing …
world's fourth most deadly cancer with almost 900 000 deaths annually. Besides an ageing …
Lifestyle and dietary environmental factors in colorectal cancer susceptibility
Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle,
as evidenced historically by migrant studies and recently by extensive epidemiologic …
as evidenced historically by migrant studies and recently by extensive epidemiologic …
The microbial landscape of colorectal cancer
MT White, CL Sears - Nature Reviews Microbiology, 2024 - nature.com
Colorectal cancer (CRC) is a substantial source of global morbidity and mortality in dire
need of improved prevention and treatment strategies. As our understanding of CRC grows …
need of improved prevention and treatment strategies. As our understanding of CRC grows …
Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals
Abstract The Tohoku Medical Megabank Organization reports the whole-genome
sequences of 1,070 healthy Japanese individuals and construction of a Japanese …
sequences of 1,070 healthy Japanese individuals and construction of a Japanese …
Determining risk of colorectal cancer and starting age of screening based on lifestyle, environmental, and genetic factors
J Jeon, M Du, RE Schoen, M Hoffmeister, PA Newcomb… - Gastroenterology, 2018 - Elsevier
Background & Aims Guidelines for initiating colorectal cancer (CRC) screening are based
on family history but do not consider lifestyle, environmental, or genetic risk factors. We …
on family history but do not consider lifestyle, environmental, or genetic risk factors. We …
Cumulative burden of colorectal cancer–associated genetic variants is more strongly associated with early-onset vs late-onset cancer
Background & Aims Early-onset colorectal cancer (CRC, in persons younger than 50 years
old) is increasing in incidence; yet, in the absence of a family history of CRC, this population …
old) is increasing in incidence; yet, in the absence of a family history of CRC, this population …
Fusobacterium nucleatum Acts as a Pro-carcinogenic Bacterium in Colorectal Cancer: From Association to Causality
S Wang, Y Liu, J Li, L Zhao, W Yan, B Lin… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is a common cancer worldwide with complex etiology.
Fusobacterium nucleatum (F. nucleatum), an oral symbiotic bacterium, has been linked with …
Fusobacterium nucleatum (F. nucleatum), an oral symbiotic bacterium, has been linked with …