Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke …

PB Gorelick, A Scuteri, SE Black, C DeCarli… - stroke, 2011 - Am Heart Assoc
Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

The importance of early brain injury after subarachnoid hemorrhage

FA Sehba, J Hou, RM Pluta, JH Zhang - Progress in neurobiology, 2012 - Elsevier
Aneurysmal subarachnoid hemorrhage (aSAH) is a medical emergency that accounts for
5% of all stroke cases. Individuals affected are typically in the prime of their lives (mean age …

Drugs for treatment of very high blood pressure during pregnancy

L Duley, S Meher, L Jones - Cochrane Database of Systematic …, 2013 - cochranelibrary.com
Background Very high blood pressure during pregnancy poses a serious threat to women
and their babies. The aim of antihypertensive therapy is to lower blood pressure quickly but …

Synthesis, utility and medicinal importance of 1, 2-& 1, 4-dihydropyridines

VK Sharma, SK Singh - RSC advances, 2017 - pubs.rsc.org
Dihydropyridine (DHP) is among the most beneficial scaffolds that have revolutionised
pharmaceutical research with unprecedented biological properties. Over the years …

L‐type calcium channel blockers and Parkinson disease in Denmark

B Ritz, SL Rhodes, L Qian, E Schernhammer… - Annals of …, 2010 - Wiley Online Library
Objective This study was undertaken to investigate L‐type calcium channel blockers of the
dihydropyridine class for association with Parkinson disease (PD), because some of these …

Prophylactic therapies for morbidity and mortality after aneurysmal subarachnoid hemorrhage: a systematic review and network meta-analysis of randomized trials

M Dayyani, B Sadeghirad, JC Grotta, S Zabihyan… - Stroke, 2022 - Am Heart Assoc
Background: Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high
mortality and morbidity. We aimed to determine the relative benefits of pharmacological …

Neuroprotection in acute ischemic stroke: a battle against the biology of nature

S Ghozy, A Reda, J Varney, AS Elhawary… - Frontiers in …, 2022 - frontiersin.org
Stroke is the second most common cause of global death following coronary artery disease.
Time is crucial in managing stroke to reduce the rapidly progressing insult of the ischemic …

Calcium channel blockers and dementia

V Nimmrich, A Eckert - British journal of pharmacology, 2013 - Wiley Online Library
Degenerative dementia is mainly caused by A lzheimer's disease and/or cerebrovascular
abnormalities. Disturbance of the intracellular calcium homeostasis is central to the …

Adjunctive therapy for severe malaria: a review and critical appraisal

R Varo, VM Crowley, A Sitoe, L Madrid, L Serghides… - Malaria journal, 2018 - Springer
Background Despite recent efforts and successes in reducing the malaria burden globally,
this infection still accounts for an estimated 212 million clinical cases, 2 million severe …

Phosphodiesterase inhibitors say NO to Alzheimer's disease

SM Nabavi, S Talarek, J Listos, SF Nabavi… - Food and Chemical …, 2019 - Elsevier
Phosphodiesterases (PDEs) consisted of 11 subtypes (PDE1 to PDE11) and over 40
isoforms that regulate levels of cyclic guanosine monophosphate (cGMP) and cyclic …