European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium

C Aldecoa, G Bettelli, F Bilotta… - European Journal of …, 2017 - journals.lww.com
The purpose of this guideline is to present evidence-based and consensus-based
recommendations for the prevention and treatment of postoperative delirium. The …

Neuroinflammation as the underlying mechanism of postoperative cognitive dysfunction and therapeutic strategies

Z Li, Y Zhu, Y Kang, S Qin, J Chai - Frontiers in cellular neuroscience, 2022 - frontiersin.org
Postoperative cognitive dysfunction (POCD) is a common neurological complication
following surgery and general anesthesia, especially in elderly patients. Severe cases delay …

Postoperative delirium: acute change with long-term implications

JL Rudolph, ER Marcantonio - Anesthesia & Analgesia, 2011 - journals.lww.com
Delirium is an acute change in cognition and attention, which may include alterations in
consciousness and disorganized thinking. Although delirium may affect any age group, it is …

Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair

FE Sieber, KJ Zakriya, A Gottschalk, MR Blute… - Mayo Clinic …, 2010 - Elsevier
OBJECTIVE To determine whether limiting intraoperative sedation depth during spinal
anesthesia for hip fracture repair in elderly patients can decrease the prevalence of …

Postoperative cognitive dysfunction after noncardiac surgery: a systematic review

S Newman, J Stygall, S Hirani, S Shaefi… - The Journal of the …, 2007 - pubs.asahq.org
This article describes a systematic review on the research into postoperative cognitive
dysfunction (POCD) in noncardiac surgery to ascertain the status of the evidence and to …

The impact of general and regional anesthesia on the incidence of post-operative cognitive dysfunction and post-operative delirium: a systematic review with meta …

SE Mason, A Noel-Storr… - Journal of Alzheimer's …, 2010 - content.iospress.com
Post-operative cognitive complications such as delirium have been consistently associated
with poor short and long term outcomes, and the role of anesthesia, particularly the role of …

New insights into the pathophysiology of postoperative cognitive dysfunction

L Krenk, LS Rasmussen… - Acta Anaesthesiologica …, 2010 - Wiley Online Library
There is evidence that postoperative cognitive dysfunction (POCD) is a significant problem
after major surgery, but the pathophysiology has not been fully elucidated. The interpretation …

Lasting effects of general anesthetics on the brain in the young and elderly:“mixed picture” of neurotoxicity, neuroprotection and cognitive impairment

L Wu, H Zhao, H Weng, D Ma - Journal of anesthesia, 2019 - Springer
General anesthetics are commonly used in major surgery. To achieve the depth of
anesthesia for surgery, patients are being subjected to a variety of general anesthetics …

Delirium and sedation in the intensive care unit: survey of behaviors and attitudes of 1384 healthcare professionals

RP Patel, M Gambrell, T Speroff, TA Scott… - Critical care …, 2009 - journals.lww.com
Objective: A 2001 survey found that most healthcare profes-sionals considered intensive
care unit (ICU) delirium as a serious problem, but only 16% used a validated delirium …

Tau phosphorylation and sevoflurane anesthesia: an association to postoperative cognitive impairment

H Le Freche, J Brouillette… - The Journal of the …, 2012 - pubs.asahq.org
Background There is a growing interest in the involvement of anesthetic agents in the
etiology of postoperative cognitive dysfunction. Recent animal studies suggest that acute …