Drug-tolerant persister (DTP) cells have attracted significant interest, given their
predominant role in treatment failure. In this respect, DTP cells reportedly survive after …

High recurrence and metastasis rates and poor prognoses are the major challenges of
current cancer therapy. Mounting evidence suggests that cancer stem cells (CSCs) play an …

Simple Summary Bromodomain and extraterminal domain (BET) proteins can regulate
cancer-related genes to make tumors grow. BMS-986158, an experimental anticancer …

Progression of early‑stage breast cancer to advanced‑stage metastatic disease represents a
major cause of death in women. Long‑term conventional and targeted therapy for breast …

Purpose Ubiquitin-conjugating enzymes E2S (UBE2S) and E2C (UBE2C), which mediate
the biological process of ubiquitination, have been widely reported in various cancers …

As an important 5‑methylcytidine (m 5 C) methyltransferase, NOP2/Sun RNA
methyltransferase family member 6 (NSUN6) has been reported to play an important role in …

Simple Summary This review is centered on the potential therapeutic utility of vitamin C (VC)
in the context of dynamic cancer evolution. Physiologically, VC has dose-dependent roles as …

Osteosarcoma is a highly malignant bone tumor derived from mesenchymal cells that
contains self-renewing cancer stem cells (CSCs), which are responsible for tumor …

Cellular plasticity can occur naturally in an organism and is considered an adapting
mechanism during the developmental stage. However, abnormal cellular plasticity is …

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer,
originating from keratinocytes of the spinous layer. Numerous risk factors have been …