The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

With the advancement of functional nanomaterials and aptamer selection technologies,
aptamer functionalized nanomaterials (AFMs) open various methods to design new sensing …

It has been more than two decades since aptamer and the systematic evolution of ligands by
exponential enrichment (SELEX) method were discovered by Larry Gold and Andrew …

Nucleic acids are the foundation of life. Specific sequences translate certain genetic traits,
protein expression, and, ultimately, cellular function. Yet, nucleic acids not only store genetic …

Conspectus Nanoparticles (NPs) have enormous potential to improve disease diagnosis
and treatment due to their intrinsic electronic, optical, magnetic, mechanical, and …

Aptamers have come in the spotlight as bio-mimetic molecular recognition elements in the
field of biomedicine due to various applications in diagnostics, drug delivery, therapeutics …

In vitro biosensors have been an integral component for early diagnosis of cancer in the
clinic. Among them, no-wash biosensors, which only depend on the simple mixing of the …

Sensitive and specific detection of tumor exosomes is of great significance for early cancer
diagnosis. In this paper, we report an aptamer strategy for exosome detection based on …

Conspectus DNA performs a vital function as a carrier of genetic code, but in the field of
nanotechnology, DNA molecules can catalyze chemical reactions in the cell, that is …

Point-of-care testing (POCT) for early diagnosis and personalized treatment in clinics plays
an increasingly important role in controlling the outbreak of disease and improving the …