Objective: A role for aberrant reward processing in the pathogenesis of depression has long
been proposed. However, no review has yet examined its role in depression by integrating …

Anhedonia is a key symptom of major depressive disorder (MDD) and comprises
behavioural deficits in three reward processing subtypes: reward liking, reward wanting, and …

Background There is well-known heterogeneity in affective mechanisms in depression that
may extend to positive affect. We used data-driven parsing of neural connectivity to reveal …

Background Heightened attention allocation toward negative‐valanced information and
reduced attention allocation toward positive‐valanced information represent viable targets …

Transcutaneous vagus nerve stimulation (tVNS) may be a promising treatment for major
depressive disorder (MDD). In this exploratory study, fMRI scans were acquired during …

Depressive disorders in youth are a significant social and public health problem. Depressed
adolescents are also at risk for school dropout and unplanned pregnancy. This chapter …

There are few reliable predictors of response to antidepressant treatments. In the present
investigation, we examined pretreatment functional brain connectivity during reward …

Aims (1) To identify trajectories of cannabis use across adolescence,(2) to measure the
influence of cannabis use characteristics on functional connectivity of the nucleus …

Major depressive disorder is a heterogeneous syndrome, of which the most common
subtype is melancholic depression (MEL). Previous studies have indicated that anhedonia is …

Accumulating behavioral and genetic research suggests that most forms of psychopathology
share common genetic and neural vulnerabilities and are manifestations of a relatively few …