Background: von Willebrand disease (VWD) is a common inherited bleeding disorder.
Significant variability exists in management options offered to patients. Objective: These …

Abstract von Willebrand disease (VWD) is the most common inherited bleeding disorder.
The disorder is characterized by excessive mucocutaneous bleeding. The most common …

The vascular endothelium has several important functions, including hemostasis. The
homeostasis of hemostasis is based on a fine balance between procoagulant and …

Background Hemophilia is a rare congenital bleeding disorder that results from complete or
partial deficiency of blood coagulation factor (F) VIII (hemophilia A) or FIX (hemophilia B) …

INTRODUCTION von Willebrand Disease (VWD), the most common inherited bleeding
disorder, is defined by decreased activity of von Willebrand Factor (VWF) activity in the …

Background Heavy menstrual bleeding occurs in 80% of women with von Willebrand
disease and is associated with iron deficiency and poor response to current therapies …

Despite von Willebrand disease (VWD) being the most common inherited bleeding disorder,
its accurate diagnosis is frequently shrouded by diagnostic pitfalls. VWD is frequently under …

Recent studies have demonstrated that only 30% of patients referred for assessment of a
possible bleeding tendency will eventually be diagnosed with a mild bleeding disorder …

Introduction von Willebrand disease (VWD) is a common bleeding disorder, which affects 1
in 100 individuals based on laboratory testing and at least 1 in 1000 individuals based on …

Background People who have or had the potential to menstruate (PPM) with inherited
bleeding disorders (BD) face particular challenges receiving appropriate diagnosis and care …