Chemistry of chitosan aerogels: three‐dimensional pore control for tailored applications

S Takeshita, S Zhao, WJ Malfait… - Angewandte Chemie …, 2021 - Wiley Online Library
Chitosan is an abundant biopolymer derived from food waste with attractive properties,
particularly its high biocompatibility and easy chemical processability. Here, we review the …

Supercritical fluid (SCF)-assisted fabrication of carrier-free drugs: an eco-friendly welcome to active pharmaceutical ingredients (APIs)

RK Kankala, PY Xu, BQ Chen, SB Wang… - Advanced Drug Delivery …, 2021 - Elsevier
Despite the success in developing various pharmaceutical formulations, most of the active
pharmaceutical ingredients (APIs)/drugs, according to the Biopharmaceutics Classification …

CO2 utilization as a supercritical solvent and supercritical antisolvent in production of sertraline hydrochloride nanoparticles

G Sodeifian, SA Sajadian, R Derakhsheshpour - Journal of CO2 Utilization, 2022 - Elsevier
Supercritical fluid (SCF) processes have attracted great attention for fabricating micro and
nanoparticles in the pharmaceutical applications. Herein we utilized, for the first time, Gas …

Solubility measurement and preparation of nanoparticles of an anticancer drug (Letrozole) using rapid expansion of supercritical solutions with solid cosolvent (RESS …

G Sodeifian, SA Sajadian - The Journal of Supercritical Fluids, 2018 - Elsevier
A method of rapid expansion of supercritical solutions with solid cosolvent (RESS-SC) was
applied, for the first time, to precipitate nanoparticles of Letrozole (LTZ). Solubility of LTZ, as …

An investigation into Sunitinib malate nanoparticle production by US-RESOLV method: Effect of type of polymer on dissolution rate and particle size distribution

F Razmimanesh, G Sodeifian, SA Sajadian - The Journal of Supercritical …, 2021 - Elsevier
The present study practiced ultrasonic-assisted rapid expansion of a supercritical CO 2
solution into a liquid solvent (US-RESOLV) process for the synthesis of nanoparticles (NPs) …

Preparation of Aprepitant nanoparticles (efficient drug for coping with the effects of cancer treatment) by rapid expansion of supercritical solution with solid cosolvent …

G Sodeifian, SA Sajadian, S Daneshyan - The Journal of Supercritical …, 2018 - Elsevier
To improve dissolution properties of aprepitant (APR) as a poorly water-soluble drug, Rapid
Expansion of Supercritical Solution with Solid Cosolvent (RESS-SC) was applied for the first …

Production of Loratadine drug nanoparticles using ultrasonic-assisted Rapid expansion of supercritical solution into aqueous solution (US-RESSAS)

G Sodeifian, SA Sajadian, NS Ardestani… - The Journal of …, 2019 - Elsevier
Abstract Effects of the process parameters such as pressure (12–30 MPa), extraction
temperature (308–338 K), nozzle length (1–7 mm), nozzle diameter (150–450 μm) and …

[HTML][HTML] Production of biopharmaceutical dried-powders using supercritical CO2 technology

A O'Sullivan, KM Ryan, L Padrela - The Journal of Supercritical Fluids, 2022 - Elsevier
The inability of many biopharmaceutical formulations to retain their structure and integrity
when in solution represents a major issue for their transport and storage, reducing their shelf …

[HTML][HTML] Solid-state and particle size control of pharmaceutical cocrystals using atomization-based techniques

A O'Sullivan, B Long, V Verma, KM Ryan… - International Journal of …, 2022 - Elsevier
Poor bioavailability and aqueous solubility represent a major constraint during the
development of new API molecules and can influence the impact of new medicines or halt …

A critical review on the particle generation and other applications of rapid expansion of supercritical solution

R Kumar, AK Thakur, N Banerjee… - International Journal of …, 2021 - Elsevier
The novel particle generation processes of Active Pharmaceutical Ingredient (API)/drug
have been extensively explored in recent decades due to their wide-range applications in …