The enteroendocrine system is the primary sensor of ingested nutrients and is responsible
for secreting an array of gut hormones, which modulate multiple physiological responses …

Food intake is detected by the chemical senses of taste and smell and subsequently by
chemosensory cells in the gastrointestinal tract that link the composition of ingested foods to …

Metformin, the most prescribed antidiabetic medicine, has shown other benefits such as anti-
ageing and anticancer effects,,–. For clinical doses of metformin, AMP-activated protein …

摘要胰高血糖素样肽‐1 (Glucagon‐like peptide‐1, GLP‐1) 是一种细胞类型特异性的胰高血糖
素原翻译后产物. 它是由胰高血糖素原基因所编码的, 在激素, 神经元以及营养的刺激下主要由肠 …

Summary Glucagon-like peptide-1 (GLP-1) is an enteric hormone that stimulates insulin
secretion and improves glycaemia in type 2 diabetes. Although GLP-1-based treatments are …

OBJECTIVE Intestinal L-cells secrete the incretin glucagon-like peptide-1 (GLP-1) in
response to ingestion of nutrients, especially long-chain fatty acids. The Gαs-coupled …

BACKGROUND AND PURPOSE The glucagon‐like peptides GLP‐1 and GLP‐2 are
secreted from enteroendocrine L‐cells following nutrient ingestion. Drugs that increase …

Background Kaempferol is a natural polyflavonol that has gained considerable attention as
antidiabetic therapeutics. Recent reports emphasize the role of hyperglycemia and …

Glucagon-like peptide-1 (GLP-1), an incretin hormone secreted primarily from the intestinal
L-cells in response to meals, modulates nutrient homeostasis via actions exerted in multiple …

Glucagon‐like peptide‐1 (GLP‐1), released from l‐cells in the intestinal epithelium, plays an
important role in postprandial glucose homeostasis and appetite control. Following the …