Over the past decade, advances in microfabrication and biomaterials have facilitated the
development of microfluidic tissue and organ models to address challenges with …

The new coronavirus SARS‐CoV‐2 is a global pandemic and a severe public health crisis.
SARS‐CoV‐2 is highly contagious and shows high mortality rates, especially in elderly and …

The vascular endothelium forms the inner lining of blood vessels and actively regulates
vascular permeability in response to chemical and physical stimuli. Understanding the …

Integrins expressed on extracellular vesicles (EVs) secreted by various cancers are reported
to mediate the organotropism of these EVs. Our previous experiment found that pancreatic …

Background and Purpose Growing evidence indicates targeting mitochondrial dynamics and
biogenesis could accelerate recovery from renal ischemia–reperfusion (I/R) injury, but the …

With the increasing morbidity and mortality, intestinal ischemia/reperfusion injury (IIRI) has
attracted more and more attention, but there is no efficient therapeutics at present. Apigenin …

Endothelial cell injury leading to microvascular rarefaction is a characteristic feature of
chronic kidney disease (CKD). However, the mechanism underlying endothelial cell dropout …

Acute kidney injury is common, with~ 13 million cases and 1.7 million deaths/year
worldwide. A major cause is renal ischaemia, typically following cardiac surgery, renal …

Albumin is the most abundant protein in blood plasma and acts as a carrier for many
circulating molecules. Hypoalbuminaemia, mostly caused by either renal or liver disease or …

Background: Vascular permeability (VP) is a fundamental aspect of vascular biology. A
growing number of studies have revealed that many signalling pathways govern VP in both …