Globally, stroke is a leading cause of death and long-term disability. Over the past decades,
several efforts have attempted to discover new drugs or repurpose existing therapeutics to …

Over the past forty years, animal models of focal cerebral ischaemia have allowed us to
identify the critical cerebral blood flow thresholds responsible for irreversible cell death …

Ischemic stroke is a devastating central nervous disease associated with oxidative stress
and NOX2 is the main source of ROS responsible for brain tissue. miRNAs are a class of …

Stroke, including cerebral ischemia, intracerebral hemorrhage, and subarachnoid
hemorrhage, is the leading cause of long-term disability and death worldwide. Animal …

Stroke is a common cause of death worldwide and leads to disability and cognitive
dysfunction. Ischemic stroke and hemorrhagic stroke are major categories of stroke …

Positron emission tomography (PET) targeting translocator protein 18 kDa (TSPO) can be
used for the noninvasive detection of neuroinflammation. Improved in vivo stability of a …

Despite the association between brainstem lesions and coma, a mechanistic understanding
of coma pathogenesis and recovery is lacking. We developed a coma model in the rat …

Cerebral ischemia/reperfusion (I/R) injury leads to neuronal damage, which may cause
disability and even mortality. Multiple studies have revealed that long non‑coding RNAs …

Background: Cerebral stroke, with ischemic stroke being its most common type, is the
leading cause of chronic disability. The ketogenic diet has been used for treating seizures …

Magnetic resonance imaging (MRI) is increasingly the method of choice for rapid stroke
assessment in patients and for guiding patient selection in clinical trials. The underlying …