Therapeutic drug monitoring (TDM) of biologics is a rapidly evolving field. We aimed to
provide a consensus statement regarding the clinical utility of TDM for biologics in …

This article has an accompanying continuing medical education activity, also eligible for
MOC credit, on page e20. Learning Objective: Upon completion of this CME activity …

Methods This document presents the official recommendations of the AGA on the medical
management of moderate to severe luminal and fistulizing CD in adults. This guideline …

Background Anti-TNF drugs are effective treatments for the management of Crohn's disease
but treatment failure is common. We aimed to identify clinical and pharmacokinetic factors …

Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic,
immunologic, and environmental influences. The incidence of Crohn's disease has steadily …

Importance Proactive therapeutic drug monitoring (TDM), defined as individualized drug
dosing based on scheduled monitoring of serum drug levels, has been proposed as an …

Crohn's disease (CD) accounts for a variety of clinical manifestations or phenotypes that
stem from chronic inflammation in the gastrointestinal tract. Its worldwide incidence is …

Abstract Background and Aims We sought to analyze whether response to a second-line
biologic varies depending on the reason for discontinuation of the primary anti-TNF agent …

Guidelines for clinical practice are intended to suggest preferable approaches to particular
medical problems as established by interpretation and collation of scientifically valid …

This article reports on the sixth scientific workshop of the European Crohn's and Colitis
Organisation [ECCO] on the pathogenesis of extraintestinal manifestations [EIMs] in …