Bacterial outer membrane vesicles as a versatile tool in vaccine research and the fight against antimicrobial resistance

Z Zhu, F Antenucci, KR Villumsen, AM Bojesen - MBio, 2021 - Am Soc Microbiol
Gram-negative bacteria include a number of pathogens that cause disease in humans and
animals. Although antibiotics are still effective in treating a considerable range of infections …

Actinobacillus pleuropneumoniae, surface proteins and virulence: a review

MM Soto Perezchica, AL Guerrero Barrera… - Frontiers in Veterinary …, 2023 - frontiersin.org
Actinobacillus pleuropneumoniae (App) is a globally distributed Gram-negative bacterium
that produces porcine pleuropneumonia. This highly contagious disease produces high …

New trends in innovative vaccine development against Actinobacillus pleuropneumoniae

A Loera-Muro, C Angulo - Veterinary microbiology, 2018 - Elsevier
Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, a
respiratory disease leading to severe economic losses in the swine industry. The most …

Outer membrane vesicles of Actinobacillus pleuropneumoniae exert immunomodulatory effects on porcine alveolar macrophages

Z Zhu, F Antenucci, HC Winther-Larsen… - Microbiology …, 2022 - Am Soc Microbiol
Outer membrane vesicles (OMVs) are spontaneously released by Gram-negative bacteria,
including Actinobacillus pleuropneumoniae, which causes contagious pleuropneumonia in …

Component Identification and Functional Analysis of Outer Membrane Vesicles Released by Avibacterium paragallinarum

C Mei, A Sun, PJ Blackall, H Xian, S Li… - Frontiers in …, 2020 - frontiersin.org
Avibacterium paragallinarum, the causative agent of infectious coryza, is known to release
outer membrane vesicles (OMVs). In the present study, we investigated the composition …

Hydrostatic Filtration Enables Large-Scale Production of Outer Membrane Vesicles That Effectively Protect Chickens against Gallibacterium anatis

F Antenucci, H Arak, J Gao, T Allahgadry, I Thøfner… - Vaccines, 2020 - mdpi.com
Gallibacterium anatis is a Gram-negative opportunistic avian pathogen representing an
emerging threat to poultry meat and egg production worldwide. To date, no vaccine able to …

Identification of novel small RNAs in extracellular vesicles produced by Actinobacillus pleuropneumoniae

GC da Silva, JN Rosa, PP Fontes… - Frontiers in …, 2023 - frontiersin.org
Extracellular vesicle (EV) production by bacteria is an important mechanism for microbial
communication and host-pathogen interaction. EVs of some bacterial species have been …

Maintenance of bacterial outer membrane lipid asymmetry: insight into MlaA

M Kaur, MP Mingeot-Leclercq - BMC microbiology, 2024 - Springer
The outer membrane (OM) of Gram-negative bacteria acts as an effective barrier to protect
against toxic compounds. By nature, the OM is asymmetric with the highly packed …

Actinobacillus pleuropneumoniae Interaction With Swine Endothelial Cells

B Plasencia-Muñoz, FJ Avelar-González… - Frontiers in Veterinary …, 2020 - frontiersin.org
Actinobacillus pleuropneumonia is a swine (host) specific respiratory pathogen and the
etiological agent of swine pleuropneumonia which affects pigs of all ages, many being …

Comparative Efficacy in Challenge Dose Models of a Toxin Expressing Whole-Cell Vaccine against Eight Serovars of Actinobacillus pleuropneumoniae in Pigs

P Mortensen, N Toft, I Kiss, V Palya, H Smits, M Tenk - Animals, 2022 - mdpi.com
Simple Summary Vaccine use is considered an integral control method to prevent
respiratory disease in pigs caused by the economically significant Actinobacillus …