Depression, with an estimated prevalence of about 40% is a most common neuropsychiatric
disorder in Parkinson disease (PD), with a negative impact on quality of life, cognitive …

Depression increasingly affects a wide range and a large number of people worldwide, both
physically and psychologically, which makes it a social problem requiring prompt attention …

Parkinson's disease (PD) is a common neurodegenerative disease implicated in multiple
interacting neurotransmitter pathways. Glutamate is the central excitatory neurotransmitter in …

Background Parkinson's disease (PD) is commonly accompanied with anxiety, multiple
studies indicate that the basolateral amygdaloid nucleus (BLA) is closely related to …

Background: Previous investigations have suggested that decreased expression of
glutamate transporter-1 (GLT-1) is involved in glutamate excitotoxicity and contribute to the …

ABSTRACT Parkinson's disease (PD), a widespread neurodegenerative disorder, often
coexists with mood disorders. Degeneration of serotonergic neurons in brainstem raphe …

Despite extensive research in recent decades, knowledge of the pathophysiology of
depression in neural circuits remains limited. Recently, the lateral habenula (LHb) has been …

Objective The aim of the present study was to investigate whether serotonin1B (5-HT1B)
receptor-adenylate cyclase (AC)-protein kinase A (PKA) signal pathway in the lateral …

The habenula (Hb) is a small structure of the posterior diencephalon that is highly conserved
across vertebrates but nonetheless has attracted relatively little research attention until the …

ABSTRACT Parkinson's disease (PD)‐related depression is associated with aberrant
neuronal oscillations and 5‐hydroxytryptamine (5‐HT) neurotransmission in the medial …