Activated ester containing polymers: opportunities and challenges for the design of functional macromolecules

A Das, P Theato - Chemical reviews, 2016 - ACS Publications
Rapidly growing demand of functional polymers in various interdisciplinary areas of
research has accentuated the need for modern synthetic tools to develop advanced …

Fluorescence correlation spectroscopy in polymer science

D Wöll - Rsc Advances, 2014 - pubs.rsc.org
Fluorescence correlation spectroscopy (FCS) is a well-established technique for studying
dynamic processes and interactions with minimal invasion into the corresponding system …

Dual Tumor Microenvironment Remodeling by Glucose‐Contained Radical Copolymer for MRI‐Guided Photoimmunotherapy

H Cheng, X Fan, E Ye, H Chen, J Yang, L Ke… - Advanced …, 2022 - Wiley Online Library
Aberrant glucose metabolism and immune evasion are recognized as two hallmarks of
cancer, which contribute to poor treatment efficiency and tumor progression. Herein, a novel …

Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy

I Negwer, A Best, M Schinnerer, O Schäfer… - Nature …, 2018 - nature.com
Nanocarrier-based drug delivery is a promising therapeutic approach that offers unique
possibilities for the treatment of various diseases. However, inside the blood stream …

Shining light on polymeric drug nanocarriers with fluorescence correlation spectroscopy

S Schmitt, L Nuhn, M Barz, HJ Butt… - Macromolecular Rapid …, 2022 - Wiley Online Library
The use of nanoparticles as carriers is an extremely promising way for administration of
therapeutic agents, such as drug molecules, proteins, and nucleic acids. Such nanocarriers …

Water-soluble polymers coupled with glycopeptide antigens and T-cell epitopes as potential antitumor vaccines.

L Nuhn, S Hartmann, B Palitzsch… - Angewandte …, 2013 - search.ebscohost.com
Highly decorated: Tumor‐associated MUC1 glycopeptide and tetanus toxoid T‐cell epitope
P2 can be attached to water‐soluble poly (N‐(2‐hydroxypropyl) methacrylamide) carriers by …

Preparing (metalla) carboranes for nanomedicine

M Gozzi, B Schwarze, E Hey‐Hawkins - ChemMedChem, 2021 - Wiley Online Library
Abstract “There's plenty of room at the bottom”(Richard Feynman, 1959): an invitation for
(metalla) carboranes to enter the (new) field of nanomedicine. For two decades, the number …

Recent progress in EPR study of spin labeled polymers and spin probed polymer systems

MA Uddin, H Yu, L Wang, KR Naveed… - Journal of Polymer …, 2020 - Wiley Online Library
The EPR technique is commonly used for the detection and characterization of
paramagnetic centers in chemical science. This method can provides a lot of information …

PEGylation of HPMA-based block copolymers enhances tumor accumulation in vivo: a quantitative study using radiolabeling and positron emission tomography

M Allmeroth, D Moderegger, D Gündel… - Journal of controlled …, 2013 - Elsevier
This paper reports the body distribution of block copolymers (made by controlled radical
polymerization) with N-(2-hydroxypropyl) methacrylamide (HPMA) as hydrophilic block and …

Post‐Polymerization Modifications to Prepare Biomedical Nanocarriers with Varying Internal Structures, their Properties and Impact on Protein Corona Formation

J Kockelmann, R Zentel, L Nuhn - … Chemistry and Physics, 2023 - Wiley Online Library
The reactive ester approach provides access to various types of drug delivery systems.
Either amphiphilic block copolymer micelles with hydrophobic cores can be generated for …