COVID-19 mechanisms in the human body—What we know so far
More than one and a half years have elapsed since the commencement of the coronavirus
disease 2019 (COVID-19) pandemic, and the world is struggling to contain it. Being caused …
disease 2019 (COVID-19) pandemic, and the world is struggling to contain it. Being caused …
Solid organ rejection following SARS-CoV-2 vaccination or COVID-19 infection: a systematic review and meta-analysis
Background: Solid organ rejection post-SARS-CoV-2 vaccination or COVID-19 infection is
extremely rare but can occur. T-cell recognition of antigen is the primary and central event …
extremely rare but can occur. T-cell recognition of antigen is the primary and central event …
Dysregulation of ACE (angiotensin-converting enzyme)-2 and renin-angiotensin peptides in SARS-CoV-2 mediated mortality and end-organ injuries
ACE (angiotensin-converting enzyme)-2 as the target for SARS-CoV-2 also negatively
regulates the renin-angiotensin system. Pathological activation of ADAM17 (A disintegrin …
regulates the renin-angiotensin system. Pathological activation of ADAM17 (A disintegrin …
Coronary microvascular dysfunction
S Godo, A Suda, J Takahashi, S Yasuda… - … , and vascular biology, 2021 - Am Heart Assoc
Over the past couple of decades, accumulating evidence has shown that structural and
functional abnormalities of coronary microvasculature are highly prevalent, associated with …
functional abnormalities of coronary microvasculature are highly prevalent, associated with …
Direct mechanisms of SARS-CoV-2-induced cardiomyocyte damage: an update
Y Yang, Z Wei, C Xiong, H Qian - Virology journal, 2022 - Springer
Myocardial injury induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) is reportedly related to disease severity and mortality, attracting attention to exploring …
2) is reportedly related to disease severity and mortality, attracting attention to exploring …
Characterisation of cardiac pathology in 23 autopsies of lethal COVID‐19
Abstract While coronavirus disease 2019 (COVID‐19) primarily affects the respiratory tract,
pathophysiological changes of the cardiovascular system remain to be elucidated. We …
pathophysiological changes of the cardiovascular system remain to be elucidated. We …
Cardiovascular disturbances in COVID-19: an updated review of the pathophysiology and clinical evidence of cardiovascular damage induced by SARS-CoV-2
Severe acute respiratory coronavirus-2 (SARS-Co-2) is the causative agent of coronavirus
disease-2019 (COVID-19). COVID-19 is a disease with highly variable phenotypes, being …
disease-2019 (COVID-19). COVID-19 is a disease with highly variable phenotypes, being …
Clinical characterization and possible pathological mechanism of acute myocardial injury in COVID-19
S Li, J Wang, Y Yan, Z Zhang, W Gong… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is a respiratory disease that can cause damage to multiple organs throughout the
body. Cardiovascular complications related to COVID-19 mainly include acute myocardial …
body. Cardiovascular complications related to COVID-19 mainly include acute myocardial …
Role of the renin-angiotensin system in long COVID's cardiovascular injuries
The renin-angiotensin system (RAS) is one of the biggest challenges of cardiovascular
medicine. The significance of the RAS in the chronic progression of SARS-CoV-2 infection …
medicine. The significance of the RAS in the chronic progression of SARS-CoV-2 infection …
Myocardial injury and altered gene expression associated with SARS-CoV-2 infection or mRNA vaccination
NL Altman, AA Berning, CE Saxon, KE Adamek… - Basic to Translational …, 2023 - jacc.org
SARS CoV-2 enters host cells via its Spike protein moiety binding to the essential cardiac
enzyme angiotensin-converting enzyme (ACE) 2, followed by internalization. COVID-19 …
enzyme angiotensin-converting enzyme (ACE) 2, followed by internalization. COVID-19 …