Understanding the impact of valproate on male fertility: insights from preclinical and clinical meta-analysis
MA Asghar, S Tang, B Wan, H Han, LP Wong… - BMC Pharmacology and …, 2024 - Springer
Background Valproic acid (VPA) is a widely used antiepileptic drug (AED) often prescribed
as a first-line treatment for many idiopathic and symptomatic generalized epilepsies. Several …
as a first-line treatment for many idiopathic and symptomatic generalized epilepsies. Several …
Nanoparticle-Mediated L-Carnitine Delivery for Improved Male Fertility
AM Moghadam, MJ Javid-Naderi, S Fathi-karkan… - Journal of Drug Delivery …, 2024 - Elsevier
Male infertility, affecting more than 40% of couples experiencing difficulties in conception, is
a significant worldwide health issue. L-Carnitine (LC) has emerged as a potential …
a significant worldwide health issue. L-Carnitine (LC) has emerged as a potential …
[HTML][HTML] Multi-pharmacological treatment for young subfertile males with chronic prostatitis/chronic pelvic pain syndrome
DH Lee, YD Yu - Investigative and Clinical Urology, 2024 - pmc.ncbi.nlm.nih.gov
Purpose This study evaluated the effectiveness of chronic prostatitis/chronic pelvic pain
syndrome (CP/CPPS) treatments using multiple pharmaceutical agents that could …
syndrome (CP/CPPS) treatments using multiple pharmaceutical agents that could …
One Factor at a Time and factorial experimental design for formulation of l-carnitine microcapsules to improve its manufacturability
MM Hegazy, AA Badawi, MA El-Nabarawi, MA Eldegwy… - Heliyon, 2024 - cell.com
Abstract l-carnitine is an essential dietary supplement of physiological importance. Handling
and manufacture of l-carnitine is difficult due to its hygroscopic nature, resulting in impairing …
and manufacture of l-carnitine is difficult due to its hygroscopic nature, resulting in impairing …
Research progress of main components from Epimedii Folium (Yinyanghuo) in the treatment of male reproductive dysfunction and application & development status of …
H Zhao, J Mei, Q Huang, H Wang, Z Xu - Journal of Ethnopharmacology, 2024 - Elsevier
Abstract Ethnopharmacological relevance Epimedii Folium (Yinyanghuo) is a commonly
used Chinese herb that plays a significant role in a lot of herbal formulae used to treat …
used Chinese herb that plays a significant role in a lot of herbal formulae used to treat …
Role of L-carnitine in Cardiovascular Health: Literature Review
R Elantary, S Othman - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality
worldwide. Secondary preventive measures, like anti-platelet medications, B-blockers, and …
worldwide. Secondary preventive measures, like anti-platelet medications, B-blockers, and …
[HTML][HTML] L-carnitine combined with traditional Chinese medicine for male infertility: A systematic review and meta-analysis
Y Yang, X Xue, J Zhou, Z Qiu, B Wang, Z Yin, G Ou… - Heliyon, 2024 - cell.com
Background Fertility rates are declining globally, and male infertility is increasingly
recognized as a significant challenge. This study aims to present the latest findings on the …
recognized as a significant challenge. This study aims to present the latest findings on the …
[PDF][PDF] Ameliorative effects of L-carnitine as an antioxidant against testicular toxicity induced by AlCl3 in male albino rats.
F Alharbi - European Review for Medical & Pharmacological …, 2024 - europeanreview.org
OBJECTIVE: The goal of this study was to investigate the potential protective effect of L-
carnitine (20 mg/kg bw, 1/20 LD 50) against aluminum chloride (AlCl3) on the quality of the …
carnitine (20 mg/kg bw, 1/20 LD 50) against aluminum chloride (AlCl3) on the quality of the …
Conserving goat sperm post-thawed gene expression and cellular characteristics using the antioxidant coenzyme Q10 supplementation
Y Oktanella, I Mustofa, FAFR An-Haru… - Veterinary …, 2024 - pmc.ncbi.nlm.nih.gov
Background and Aim: The use of frozen goat semen for artificial insemination frequently
results in a decline in sperm quality following thawing, which can be attributed to cold shock …
results in a decline in sperm quality following thawing, which can be attributed to cold shock …
Chronic oral administration of L-carnitine induces testicular injury: in vivo evidence
L Ran, R Zhao, G Hu, G Dai, Q Yao, C Chen… - … Urology and Nephrology, 2024 - Springer
Purpose While L-carnitine is commonly used to treat oligoasthenozoospermia, concerns
have been raised regarding its potential harm to spermatogenesis. This study aims to …
have been raised regarding its potential harm to spermatogenesis. This study aims to …