Low drug bioavailability, which is mostly a result of poor aqueous drug solubilities and of
inadequate drug dissolution rates, is one of the most significant challenges that …

Supercritical carbon dioxide (SC‐CO2) is CO2 that is stored beyond its critical point of 7.4
MPa and 31.1° C. Given the request for consumption of a green solvent for the environment …

Supercritical fluids possess the unique properties of behaving like liquids and gases, above
their critical point. Supercritical fluid technology has recently emerged as a green and novel …

Despite the success in developing various pharmaceutical formulations, most of the active
pharmaceutical ingredients (APIs)/drugs, according to the Biopharmaceutics Classification …

Peach almonds contain oil with important therapeutic and nutritional properties due to the
presence of unsaturated fatty acids, high content of oleic acid and other substances. In this …

In order to improve the dissolution properties of poorly water-soluble drugs, some drugs
were subjected to micronization or prepared as composite particles using supercritical fluid …

Supercritical fluid extraction (SFE), which has received much interest in its use and further
development for industrial applications, is a method that offers some advantages over …

A significant majority of the 20 approved nanoformulations consist predominantly of
nanocrystals (NCs). NCs are nanosized drug moieties comprising 100% of the drug with …

Mango leaves contain high levels of phenolic compounds, such as mangiferin which have
multiple antioxidant and pharmaceutical properties and great potential in nutraceutical …

Literature data on basic research for and practical application of the synthesis of micro-and
nanoparticles with the use of supercritical fluids (SCFs) are systematized and analyzed. The …