TMS-induced silent periods: A review of methods and call for consistency

KE Hupfeld, CW Swanson, BW Fling… - Journal of neuroscience …, 2020 - Elsevier
Transcranial magnetic stimulation (TMS)-induced silent periods provide an in vivo measure
of human motor cortical inhibitory function. Cortical silent periods (cSP, also sometimes …

Aging and motor inhibition: a converging perspective provided by brain stimulation and imaging approaches

O Levin, H Fujiyama, MP Boisgontier… - Neuroscience & …, 2014 - Elsevier
The ability to inhibit actions, one of the hallmarks of human motor control, appears to decline
with advancing age. Evidence for a link between changes in inhibitory functions and poor …

Older adults exhibit more intracortical inhibition and less intracortical facilitation than young adults

M McGinley, RL Hoffman, DW Russ, JS Thomas… - Experimental …, 2010 - Elsevier
BACKGROUND: Aging results in decreased neuromuscular function, which is likely
associated with neurologic alterations. At present little is known regarding age-related …

A meta-analysis of the effects of aging on motor cortex neurophysiology assessed by transcranial magnetic stimulation

A Bhandari, N Radhu, F Farzan, BH Mulsant… - Clinical …, 2016 - Elsevier
Objective Transcranial magnetic stimulation (TMS) is a non-invasive tool used for studying
cortical excitability and plasticity in the human brain. This review aims to quantitatively …

Evidence for motor cortex dedifferentiation in older adults

JA Bernard, RD Seidler - Neurobiology of aging, 2012 - Elsevier
Older adults (OA) show more diffuse brain activity than young adults (YA) during the
performance of cognitive, motor, and perceptual tasks. It is unclear whether this …

Fundamental differences in callosal structure, neurophysiologic function, and bimanual control in young and older adults

BW Fling, RD Seidler - Cerebral Cortex, 2012 - academic.oup.com
Bimanual actions involve coordinated motion but often rely on the movements performed
with each hand to be different. Older adults exhibit differentially greater variability for …

[HTML][HTML] The role of neuromuscular changes in aging and knee osteoarthritis on dynamic postural control

J Takacs, MG Carpenter, SJ Garland… - Aging and disease, 2013 - ncbi.nlm.nih.gov
Knee osteoarthritis (OA) is a chronic joint condition, with 30% of those over the age of 75
exhibiting severe radiographic disease. Nearly 50% of those with knee OA have …

Differential behavioral and physiological effects of anodal transcranial direct current stimulation in healthy adults of younger and older age

KF Heise, M Niehoff, JF Feldheim, G Liuzzi… - Frontiers in aging …, 2014 - frontiersin.org
Changes in γ-aminobutyric acid (GABA) mediated synaptic transmission have been
associated with age-related motor and cognitive functional decline. Since anodal …

GABA levels and measures of intracortical and interhemispheric excitability in healthy young and older adults: an MRS-TMS study

L Hermans, O Levin, C Maes, P van Ruitenbeek… - Neurobiology of …, 2018 - Elsevier
Edited magnetic resonance spectroscopy (MRS) and transcranial magnetic stimulation
(TMS) have often been used to study the integrity of the GABAergic neurotransmission …

Differential callosal contributions to bimanual control in young and older adults

BW Fling, CM Walsh, AS Bangert… - Journal of cognitive …, 2011 - direct.mit.edu
Our recent work has shown that older adults are disproportionately impaired at bimanual
tasks when the two hands are moving out of phase with each other [Bangert, AS, Reuter …