Background Of the many antimicrobial agents available, iodophore-based formulations such
as povidone iodine have remained popular after decades of use for antisepsis and wound …

Objectives: Using antiseptics in wound care can promote healing by preventing and treating
infection. However, using antiseptics can present many challenges, including issues with …

Biofilms play a major role in delaying chronic wounds from healing. A wound infiltrated with
biofilm, or “critically colonised” wound, may become clinically infected if the number of …

Introduction: Chlorhexidine gluconate (CHX) is widely used as a preoperative surgical skin-
preparation solution and intra-wound irrigation agent, with excellent efficacy against wide …

Background Thorough irrigation and debridement using an irrigation solution is a well-
established treatment for both acute and chronic periprosthetic joint infections (PJIs). In the …

Background: Povidone-iodine (PI) irrigation is often used prior to wound closure in total joint
arthroplasty, but there are limited reports evaluating its efficacy in decreasing joint infections …

Prosthetic joint infection (PJI) is a serious complication after total joint arthroplasty (TJA).
Chlorhexidine is a widely used antiseptic because of its rapid and persistent action. It is well …

Abstract Purpose of Review The associated patient morbidity and resource-intensive nature
of managing surgical site infections (SSI) has focused attention toward not only improving …

Background: Postoperative infection remains a major challenge in revision total hip
arthroplasty (THA) and revision total knee arthroplasty (TKA). Wound irrigation with dilute …

Introduction Surgical site infection (SSI) remains a significant source of morbidity in spine
surgery, with reported rates varying from 0.7 to 16%. Objective To systematically review and …