The developing utility of zebrafish models of neurological and neuropsychiatric disorders: A critical review

BD Fontana, NJ Mezzomo, AV Kalueff… - Experimental …, 2018 - Elsevier
Zebrafish (Danio rerio) have become a powerful tool in neuroscience research due to their
genetic tractability, molecular/physiological conservation, small body size, ease of …

The zebrafish for preclinical psilocybin research

OA Syed, B Tsang, R Gerlai - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
In this review, we discuss the possible utility of zebrafish in research on psilocybin, a
psychedelic drug whose recreational use as well as possible clinical application are gaining …

Environmental enrichment modulates the response to chronic stress in zebrafish

M Marcon, R Mocelin, R Benvenutti… - Journal of …, 2018 - journals.biologists.com
Several studies have shown that manipulations to the housing environment modulate
susceptibility to stress in laboratory animals, mainly in rodents. Environmental enrichment …

[HTML][HTML] Understanding how stress responses and stress-related behaviors have evolved in zebrafish and mammals

MS de Abreu, KA Demin, ACVV Giacomini… - Neurobiology of …, 2021 - Elsevier
Stress response is essential for the organism to quickly restore physiological homeostasis
disturbed by various environmental insults. In addition to well-established physiological …

Understanding neurobehavioral effects of acute and chronic stress in zebrafish

KA Demin, AS Taranov, NP Ilyin, AM Lakstygal… - Stress, 2021 - Taylor & Francis
Stress is a common cause of neuropsychiatric disorders, evoking multiple behavioral,
endocrine and neuro-immune deficits. Animal models have been extensively used to …

Effects of acute and chronic arecoline in adult zebrafish: Anxiolytic-like activity, elevated brain monoamines and the potential role of microglia

N Serikuly, ET Alpyshov, DM Wang, JT Wang… - Progress in Neuro …, 2021 - Elsevier
Arecoline is a naturally occurring psychoactive alkaloid with partial agonism at nicotinic and
muscarinic acetylcholine receptors. Arecoline consumption is widespread, making it the …

Current state of modeling human psychiatric disorders using zebrafish

FV Costa, TO Kolesnikova, DS Galstyan… - International Journal of …, 2023 - mdpi.com
Psychiatric disorders are highly prevalent brain pathologies that represent an urgent, unmet
biomedical problem. Since reliable clinical diagnoses are essential for the treatment of …

Zebrafish as an animal model for testing agents with antidepressant potential

J Lachowicz, K Niedziałek, E Rostkowska, A Szopa… - Life, 2021 - mdpi.com
Depression is a serious mental disease that, according to statistics, affects 320 million
people worldwide. Additionally, a current situation related to the COVID-19 pandemic has …

High-glucose/high-cholesterol diet in zebrafish evokes diabetic and affective pathogenesis: The role of peripheral and central inflammation, microglia and apoptosis

JJ Wang, YJ Li, K Lai, QM Zhong, KA Demin… - Progress in Neuro …, 2020 - Elsevier
Neuroinflammation and metabolic deficits contribute to the etiology of human affective
disorders, such as anxiety and depression. The zebrafish (Danio rerio) has recently …

Effect of aerobic exercise as a treatment on type 2 diabetes mellitus with depression-like behavior zebrafish

L Wang, J Ma, W Wu, Y Fang, F Liu, Q Yang, X Hu… - Life Sciences, 2022 - Elsevier
Background Depression is the most known complication of type 2 diabetes mellitus (T2DM).
Aerobic exercise improves glycemic control in T2DM, although the underlying mechanisms …