Hemorrhagic stroke is a common and severe neurological disorder and is associated with
high rates of mortality and morbidity, especially for intracerebral hemorrhage (ICH) …

Temperature stress is one of the crucial factors determining geographical distribution of
insect species. Most of them are active in moderate temperatures, however some are …

Cold static preservation on ice (~ 4° C) remains the clinical standard of donor organ
preservation. However, mitochondrial injury develops during prolonged storage, which limits …

Mitochondrial toxicity is an important safety endpoint in drug discovery. Models based solely
on chemical structure for predicting mitochondrial toxicity are currently limited in accuracy …

It is now well known that oxidative stress promotes lipid peroxidation, protein oxidation,
activation of proteases, fragmentation of DNA and alteration in gene expression for …

Familial hemiplegic migraine is an episodic neurological disorder characterized by transient
sensory and motor symptoms and signs. Mutations of the ion pump α2-Na/K ATPase cause …

Arsenic is a potent cardiovascular toxicant associated with numerous biomarkers of
cardiovascular diseases in exposed human populations. Arsenic is also a carcinogen, yet …

A limiting factor in the therapeutic outcome of children with high-risk neuroblastoma is the
intrinsic and acquired resistance to common chemotherapeutic treatments. Here we …

In this study, several lines of evidence are provided to show that Na+, K+-ATPase activity
exerts vital roles in normal brain development and function and that loss of enzyme activity is …

Objective To investigate the changes of ambulatory electrocardiography and peripheral
blood SOD, MDA and Na+-K+-ATP enzymes in patients of acute myocardial infarction (AMI) …