Human immunodeficiency virus (HIV) especially HIV-1 infection and its progression to
acquired immune deficiency syndrome (AIDS) remains a significant global health challenge …

The significant threat to humanity is HIV infection, and it is uncertain whether a definitive
treatment or a safe HIV vaccine is. HIV-1 is continually evolving and resistant to commonly …

A continuous-flow preparation of 2-benzoxazolinone via the Hofmann rearrangement of
salicylamide has been implemented employing trichloroisocyanuric acid as the stable and …

In the framework of the multitarget inhibitor study, we report an in silico analysis of 1, 2-
dibenzoylhydrazine (DBH) with respect to three essential receptors such as the ecdysone …

Catalytic intramolecular C–H amination and aziridination reactions of o-allylphenyl
azidoformates have been achieved under visible-light irradiation, providing a mild, clean …

Abstract Paraoxonase 1 (PON1), an esterase linked to high‐density lipoprotein (HDL), is
known to have strong antioxidant and anti‐cardiovascular properties. In this study, eleven …

Background: The emergence of drug-resistant viral strains has created the need for the
development of novel anti-HIV agents with a diverse structure that targets key enzymes in …

In the present study, 24 kinds of 2-arylamino-5-substituteddisulfanyl-1, 3, 4-thiadiazoles
were prepared through multistep synthesis. The structures of synthesized compounds were …

Design, Synthesis, Molecular Modeling, In Silico ADME Studies and Anti-HIV-1 Assay of New
Diazocoumarin Derivatives - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

A series of 2-benzoxazolinone, diazocoumarin and quinazoline derivatives have been
shown to inhibit HIV replication in cell culture. To understand the pharmacophore properties …