The resolution of the inflammatory response is highly regulated by the timely biosynthesis of
a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers …

The lung is ventilated by thousand liters of air per day. Inevitably, the respiratory system
comes into contact with airborne microbial compounds, most of them harmless …

Nasal irrigation (NI) is an old practice of upper respiratory tract care that likely originated in
the Ayurvedic medical tradition. It is used alone or in association with other therapies in …

The resolution of inflammation (RoI), once believed to be a passive process, has lately been
shown to be an active and delicately orchestrated process. During the resolution phase of …

Nasal irrigation plays a non-negligible role in the treatment of numerous sinonasal
pathologies and postoperative care. There is, however, a wide variety of protocols. The …

Airborne pathogens and environmental stimuli evoke immune responses in the lung. It is
critical to health that these responses be controlled to prevent tissue damage and the …

Maintenance of normal epithelial ion and water transport in the lungs includes providing a
thin layer of surface liquid that coats the conducting airways. This airway surface liquid is …

CFTR is a cAMP-activated chloride and bicarbonate channel that is critical for lung
homeostasis. Decreases in CFTR expression have dire consequences in cystic fibrosis (CF) …

Inflammation is an a physiological response instead an essential response of the organism
to injury and its adequate resolution is essential to restore homeostasis. However, defective …

Non-resolving inflammation is the main mechanism of morbidity and mortality among
patients suffering from cystic fibrosis (CF), the most common life-threatening human genetic …