Rescue of sharp wave-ripples and prevention of network hyperexcitability in the ventral but not the dorsal hippocampus of a rat model of fragile X syndrome
LJ Leontiadis, G Trompoukis, G Tsotsokou… - Frontiers in cellular …, 2023 - frontiersin.org
Fragile X syndrome (FXS) is a genetic neurodevelopmental disorder characterized by
intellectual disability and is related to autism. FXS is caused by mutations of the fragile X …
intellectual disability and is related to autism. FXS is caused by mutations of the fragile X …
Luteolin ameliorates chronic stress-induced depressive-like behaviors in mice by promoting the Arginase-1+ microglial phenotype via a PPARγ-dependent …
N Yuan, W Zhu, Q Ma, M Huang, R Huo… - Acta Pharmacologica …, 2024 - nature.com
Accumulating evidence shows that neuroinflammation substantially contributes to the
pathology of depression, a severe psychiatric disease with an increasing prevalence …
pathology of depression, a severe psychiatric disease with an increasing prevalence …
Multivariate sharp‐wave ripples in schizophrenia during awake state
Aims Schizophrenia (SZ) is a brain disorder characterized by psychotic symptoms and
cognitive dysfunction. Recently, irregularities in sharp‐wave ripples (SPW‐Rs) have been …
cognitive dysfunction. Recently, irregularities in sharp‐wave ripples (SPW‐Rs) have been …
[HTML][HTML] Haploinsufficiency of intraflagellar transport protein 172 causes autism-like behavioral phenotypes in mice through BDNF
N Zheng, S Luo, X Zhang, L Hu, M Huang, M Li… - Journal of Advanced …, 2024 - Elsevier
Introduction Primary cilia are hair-like solitary organelles growing on most mammalian cells
that play fundamental roles in embryonic patterning and organogenesis. Defective cilia often …
that play fundamental roles in embryonic patterning and organogenesis. Defective cilia often …
Social and nonsocial environmental loss have differential effects on ventral hippocampus-dependent behavior and inhibitory synaptic markers in adult male mice
IR Gore, CJ Brown, RC Waters, E Gould - Learning & Memory, 2024 - learnmem.cshlp.org
In humans, psychological loss, whether social or nonsocial, can lead to clinical depression,
anxiety disorders, and social memory impairments. Researchers have modeled combined …
anxiety disorders, and social memory impairments. Researchers have modeled combined …
The defects of the hippocampal ripples and theta rhythm in depression, and the effects of physical exercise on their amelioration
S Koketsu, K Matsubara, Y Ueki, Y Shinohara, K Inoue… - Heliyon, 2024 - cell.com
Adverse environmental stress causes depressive symptoms with the impairments of memory
formation, cognition, and motivation, however, their underlying neural bases have not been …
formation, cognition, and motivation, however, their underlying neural bases have not been …
Comparison of three common inbred mouse strains reveals substantial differences in hippocampal GABAergic interneuron populations and in vitro network …
G Çalışkan, YE Demiray, O Stork - European Journal of …, 2023 - Wiley Online Library
A major challenge in neuroscience is to pinpoint neurobiological correlates of specific
cognitive and neuropsychiatric traits. At the mesoscopic level, promising candidates for …
cognitive and neuropsychiatric traits. At the mesoscopic level, promising candidates for …