Laboratory biomarkers for diagnosis and prognosis in COVID-19

D Battaglini, M Lopes-Pacheco… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) causes a wide spectrum of
clinical manifestations, with progression to multiorgan failure in the most severe cases …

The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

DNA-framework-based multidimensional molecular classifiers for cancer diagnosis

F Yin, H Zhao, S Lu, J Shen, M Li, X Mao, F Li… - Nature …, 2023 - nature.com
A molecular classification of diseases that accurately reflects clinical behaviour lays the
foundation of precision medicine. The development of in silico classifiers coupled with …

Impact of COVID-19 on cardiovascular disease

I Vosko, A Zirlik, H Bugger - Viruses, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a viral infection with the novel severe acute
respiratory distress syndrome corona virus 2 (SARS-CoV-2). Until now, more than 670 …

Pathophysiological mechanisms of thrombosis in acute and long COVID-19

H Jing, X Wu, M Xiang, L Liu, VA Novakovic… - Frontiers in …, 2022 - frontiersin.org
COVID-19 patients have a high incidence of thrombosis, and thromboembolic complications
are associated with severe COVID-19 and high mortality. COVID-19 disease is associated …

Understanding long COVID; mitochondrial health and adaptation—old pathways, new problems

AVW Nunn, GW Guy, W Brysch, JD Bell - Biomedicines, 2022 - mdpi.com
Many people infected with the SARS-CoV-2 suffer long-term symptoms, such as “brain fog”,
fatigue and clotting problems. Explanations for “long COVID” include immune imbalance …

Bleeding and thrombotic events in patients with severe COVID-19 supported with extracorporeal membrane oxygenation: a nationwide cohort study

A Mansour, E Flecher, M Schmidt, B Rozec… - Intensive Care …, 2022 - Springer
Purpose To describe bleeding and thrombotic events and their risk factors in patients
receiving extracorporeal membrane oxygenation (ECMO) for severe coronavirus disease …

Clinical quantitative coronary artery stenosis and coronary atherosclerosis imaging: a Consensus Statement from the Quantitative Cardiovascular Imaging Study …

AJV Mézquita, F Biavati, V Falk, H Alkadhi… - Nature Reviews …, 2023 - nature.com
The detection and characterization of coronary artery stenosis and atherosclerosis using
imaging tools are key for clinical decision-making in patients with known or suspected …

Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs

P Weeratunga, L Denney, JA Bull, E Repapi… - Nature …, 2023 - nature.com
Single cell spatial interrogation of the immune-structural interactions in COVID− 19 lungs is
challenging, mainly because of the marked cellular infiltrate and architecturally distorted …

Endotheliopathy in acute COVID-19 and long COVID

AG Vassiliou, CS Vrettou, C Keskinidou… - International Journal of …, 2023 - mdpi.com
The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …