Improving the prognosis of health care in the USA

AP Galvani, AS Parpia, EM Foster, BH Singer… - The Lancet, 2020 - thelancet.com
Although health care expenditure per capita is higher in the USA than in any other country,
more than 37 million Americans do not have health insurance, and 41 million more have …

The pre-exposure prophylaxis (PrEP) care cascade in people who inject drugs: a systematic review

CB Mistler, MM Copenhaver, R Shrestha - AIDS and Behavior, 2021 - Springer
Injection drug use is a key risk factor for the transmission of HIV. Prevention strategies, such
as the use of pre-exposure prophylaxis (PrEP), are effective at reducing the risk of HIV …

Methadone access for opioid use disorder during the COVID-19 pandemic within the United States and Canada

PJ Joudrey, ZM Adams, P Bach, S Van Buren… - JAMA Network …, 2021 - jamanetwork.com
Importance Methadone access may be uniquely vulnerable to disruption during COVID-19,
and even short delays in access are associated with decreased medication initiation and …

[HTML][HTML] Opioid overdose

EY Schiller, A Goyal, OJ Mechanic - 2017 - europepmc.org
Objectives: Review the current opioid epidemic in the USA. Describe the mode of action of
the opiates. Summarize ways to prevent and manage opiate toxicity and overdose. Explain …

Association between increased dispensing of opioid agonist therapy take-home doses and opioid overdose and treatment interruption and discontinuation

T Gomes, TJ Campbell, SA Kitchen, R Garg, N Bozinoff… - Jama, 2022 - jamanetwork.com
Importance During the COVID-19 pandemic, modified guidance for opioid agonist therapy
(OAT) allowed prescribers to increase the number of take-home doses to promote treatment …

Barriers and facilitators to a novel low-barrier hydromorphone distribution program in Vancouver, Canada: a qualitative study

A Ivsins, J Boyd, S Mayer, A Collins… - Drug and alcohol …, 2020 - Elsevier
Abstract Background North America is experiencing an overdose crisis driven by illicitly-
manufactured fentanyl, related analogues, and fentanyl-adulterated drugs. The concept of …

Opioid use disorder and treatment: challenges and opportunities

KA Hoffman, J Ponce Terashima, D McCarty - BMC health services …, 2019 - Springer
Background Addiction health service researchers have focused efforts on opioid use
disorder (OUD) and strategies to address the emerging public health threats associated with …

Transitions in care between hospital and community settings for individuals with a substance use disorder: A systematic review

H James, J Morgan, L Ti, S Nolan - Drug and Alcohol Dependence, 2023 - Elsevier
Background and aims Individuals with a substance use disorder (SUD) have high rates of
hospital service utilization including emergency department (ED) presentations and hospital …

Barriers and facilitators to opioid agonist therapy in rural and remote communities in Canada: an integrative review

EM Pijl, A Alraja, E Duff, C Cooke, S Dash… - … , prevention, and policy, 2022 - Springer
Background People living in rural and remote communities in Canada are often
disproportionately impacted by opioid use disorder. When compared to urban centres, rural …

Relative effectiveness of medications for opioid-related disorders: a systematic review and network meta-analysis of randomized controlled trials

J Lim, I Farhat, A Douros, D Panagiotoglou - PLoS One, 2022 - journals.plos.org
Introduction Several pharmacotherapeutic interventions are available for maintenance
treatment for opioid-related disorders. However, previous meta-analyses have been limited …