Objective: To provide a broad overview of the state of drug misuse research, particularly
focusing on opioid drug use in the USA Design: An overview of published reviews of the …

Preventing the transition to injection drug use is an important public health goal, as people
who inject drugs (PWID) are at high risk for overdose and acquisition of infectious disease …

Background Opioid agonist treatment (OAT) is an effective biomedical intervention to
manage opioid use disorder among persons who inject drugs (PWID). Preliminary evidence …

Introduction We sought to identify latent profiles of polysubstance use patterns among
people who inject drugs in three distinct North American settings, and then determine …

Objective: Drug injection initiation is often assisted by a person who injects drugs (PWID).
How often PWID provide this assistance has not been examined. We examine frequency of …

Injection drug initiation usually requires assistance by someone who already injects drugs.
To develop interventions that prevent people from starting to inject drugs, it is imperative to …

Background Injection drug use (IDU) is associated with multiple health harms. The vast
majority of IDU initiation events (in which injection-naïve persons first adopt IDU) are …

Women's initiation into injection drug use often establishes a pattern of risk following first
injection. This study explored sources of gendered power dynamics in injection initiation …

Despite the proliferation of fentanyl and fentanyl-adulterated opioids in North America, the
impacts of this drug market change on injection initiation processes have not been …

Background The social processes around initiating injection may be well-suited to
intervention, yet there is substantial heterogeneity in the reported experiences of people …