Epigenetics of early cardiometabolic disease: mechanisms and precision medicine
AA Baccarelli, J Ordovás - Circulation Research, 2023 - Am Heart Assoc
Epigenetics has transformed our understanding of the molecular basis of complex diseases,
including cardiovascular and metabolic disorders. This review offers a comprehensive …
including cardiovascular and metabolic disorders. This review offers a comprehensive …
Single-Nucleotide Resolution Mapping of N6-Methyladenine in Genomic DNA
CJ Ma, G Li, WX Shao, YH Min, P Wang… - ACS Central …, 2023 - ACS Publications
N 6-Methyladenine (6mA) is a naturally occurring DNA modification in both prokaryotes and
eukaryotes. Herein, we developed a deaminase-mediated sequencing (DM-seq) method for …
eukaryotes. Herein, we developed a deaminase-mediated sequencing (DM-seq) method for …
Shaping eukaryotic epigenetic systems by horizontal gene transfer
IR Arkhipova, IA Yushenova, F Rodriguez - BioEssays, 2023 - Wiley Online Library
DNA methylation constitutes one of the pillars of epigenetics, relying on covalent bonds for
addition and/or removal of chemically distinct marks within the major groove of the double …
addition and/or removal of chemically distinct marks within the major groove of the double …
Quantitative analysis of N6-methyladenine at single-base resolution in mitochondrial DNA of hepatocellular carcinoma by deaminase-mediated sequencing
WX Shao, J Wu, G Li, YH Min, QS Hu, Y Liu, W Ci… - Chinese Chemical …, 2024 - Elsevier
ABSTRACT N 6-methyladenine (6mA) is a prevalent DNA modification and is involved in a
wide range of human diseases. Previous studies have indicated that 6mA is enriched in …
wide range of human diseases. Previous studies have indicated that 6mA is enriched in …
Transcriptome-wide profiling of N 6-methyladenosine via a selective chemical labeling method
Y Xie, S Han, Q Li, Z Fang, W Yang, Q Wei, Y Wang… - Chemical …, 2022 - pubs.rsc.org
Studies of chemical modifications on RNA have ushered in the field of epitranscriptomics.
N6-Methyladenosine (m6A) is the most typical RNA modification and is indispensable for …
N6-Methyladenosine (m6A) is the most typical RNA modification and is indispensable for …
Circulating tumor DNA methylation detection as biomarker and its application in tumor liquid biopsy: advances and challenges
L Li, Y Sun - MedComm, 2024 - Wiley Online Library
Circulating tumor DNA (ctDNA) methylation, an innovative liquid biopsy biomarker, has
emerged as a promising tool in early cancer diagnosis, monitoring, and prognosis …
emerged as a promising tool in early cancer diagnosis, monitoring, and prognosis …
Quantitative profiling of DNA 6mA at single-base resolution using NAME-seq
Abstract DNA N6-methyladenine (6mA) is prokaryotes' most prevalent type of DNA
methylation. Recently, 6mA has been identified in eukaryotic genomes, but the prevalence …
methylation. Recently, 6mA has been identified in eukaryotic genomes, but the prevalence …
Selective Chemical Reactions for Nucleic Acid Sequencing and DNA-Encoded Library Synthesis
Y Mahdavi Amiri - 2022 - yorkspace.library.yorku.ca
Abstract Part One: The ability to map methylation sites in the human genome and
epitranscriptome has transformed our understanding of how these modifications govern and …
epitranscriptome has transformed our understanding of how these modifications govern and …